RAD51B
RAD51 paralog B
R51H2, RAD51L1, REC2
Human RAD51B (5890), Mouse Rad51b (19363), Rat Rad51b (500679), domestic guinea pig Rad51b (100713111), naked mole-rat Rad51b (101714221), cow RAD51B (617007), sheep RAD51B (101116317), dog RAD51B (490746), Thale Cress RAD51B (817404), Zebrafish rad51b (406721)
- Human(5890) Summary: The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are evolutionarily conserved proteins essential for DNA repair by homologous recombination. This protein has been shown to form a stable heterodimer with the family member RAD51C, which further interacts with the other family members, such as RAD51, XRCC2, and XRCC3. Overexpression of this gene was found to cause cell cycle G1 delay and cell apoptosis, which suggested a role of this protein in sensing DNA damage. At least three alternatively spliced transcript variants encoding distinct isoforms have been observed. Rearrangements between this locus and high mobility group AT-hook 2 (HMGA2, GeneID 8091) have been observed in uterine leiomyomata. [provided by RefSeq, Jul 2011]
- Mouse(19363) RAD51 homolog B
- Rat(500679) RAD51 paralog B
- domestic guinea pig(100713111) RAD51 homolog B (S. cerevisiae)
- naked mole-rat(101714221) RAD51 homolog B (S. cerevisiae)
- cow(617007) RAD51 homolog B (S. cerevisiae)
- sheep(101116317) RAD51 homolog B (S. cerevisiae)
- dog(490746) RAD51 homolog B (S. cerevisiae)
- Thale Cress(817404) DNA repair protein RAD51B
- Zebrafish(406721) RAD51 homolog B (S. cerevisiae)
- chicken(769071) RAD51 homolog B (S. cerevisiae)
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