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Merck

PDE1A

phosphodiesterase 1A, calmodulin-dependent

Synonymes:
CAM-PDE-1A, HCAM-1, HCAM1, HSPDE1A
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(5136) Summary: Cyclic nucleotide phosphodiesterases (PDEs) play a role in signal transduction by regulating intracellular cyclic nucleotide concentrations through hydrolysis of cAMP and/or cGMP to their respective nucleoside 5-prime monophosphates. Members of the PDE1 family, such as PDE1A, are Ca(2+)/calmodulin (see CALM1; MIM 114180)-dependent PDEs (CaM-PDEs) that are activated by calmodulin in the presence of Ca(2+) (Michibata et al., 2001 [PubMed 11342109]
  • Mouse(18573) phosphodiesterase 1A, calmodulin-dependent
  • Rat(81529) phosphodiesterase 1A, calmodulin-dependent
  • chicken(424116) phosphodiesterase 1A, calmodulin-dependent
  • Zebrafish(564465) phosphodiesterase 1A, calmodulin-dependent
  • domestic cat(101083101) phosphodiesterase 1A, calmodulin-dependent
  • dog(403652) phosphodiesterase 1A, calmodulin-dependent
  • naked mole-rat(101712147) phosphodiesterase 1A, calmodulin-dependent
  • sheep(101119369) phosphodiesterase 1A, calmodulin-dependent
  • Domestic Rabbit(100346878) phosphodiesterase 1A, calmodulin-dependent
  • cow(281969) phosphodiesterase 1A, calmodulin-dependent
  • Horse(100054082) phosphodiesterase 1A, calmodulin-dependent
  • domestic guinea pig(100527956) phosphodiesterase 1A, calmodulin-dependent

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Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-PDE1A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry
western blot
Anti-PDE1A antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
western blot
Anti-PDE1A antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human, mouse
Application
western blot

Small Molecule - Inhibitor

Référence du produit
Description
Espèce(s)
8-Methoxymethyl-3-isobutyl-1-methylxanthine, ≥98%,
Espèce(s)
human
Vinpocetine, ≥98%, solid,
Espèce(s)
human
Dipyridamole, United States Pharmacopeia (USP) Reference Standard,
Espèce(s)
human
Dipyridamole impurity standard, British Pharmacopoeia (BP) Reference Standard,
Espèce(s)
human
Dipyridamole, British Pharmacopoeia (BP) Reference Standard,
Espèce(s)
human

Proteins

Référence du produit
Description
Espèce(s)
PDE1A Active human, recombinant, expressed in baculovirus infected insect cells, ≥70% (SDS-PAGE),
Espèce(s)
human

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human PDE1A,
Espèce(s)
human
MISSION® esiRNA, targeting mouse Pde1a,
Espèce(s)
mouse