Accéder au contenu
Merck

PCSK2

proprotein convertase subtilisin/kexin type 2

Synonymes:
NEC 2, NEC-2, NEC2, PC2, SPC2
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(5126) Summary: This gene encodes a member of the subtilisin-like proprotein convertase family. These enzymes process latent precursor proteins into their biologically active products. The encoded protein plays a critical role in hormone biosynthesis by processing a variety of prohormones including proinsulin, proopiomelanocortin and proluteinizing-hormone-releasing hormone. Single nucleotide polymorphisms in this gene may increase susceptibility to myocardial infarction and type 2 diabetes. This gene may also play a role in tumor development and progression. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]
  • Mouse(18549) proprotein convertase subtilisin/kexin type 2
  • Rat(25121) proprotein convertase subtilisin/kexin type 2
  • Zebrafish(100004460) proprotein convertase subtilisin/kexin type 2
  • domestic cat(101098130) proprotein convertase subtilisin/kexin type 2
  • naked mole-rat(101710029) proprotein convertase subtilisin/kexin type 2
  • domestic guinea pig(100727607) proprotein convertase subtilisin/kexin type 2
  • chicken(395136) proprotein convertase subtilisin/kexin type 2
  • dog(485757) proprotein convertase subtilisin/kexin type 2
  • Domestic Rabbit(100358339) proprotein convertase subtilisin/kexin type 2
  • Horse(100050755) proprotein convertase subtilisin/kexin type 2
  • cow(281968) proprotein convertase subtilisin/kexin type 2

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

ELISA

Référence du produit
Description
Espèce(s)
Human PCSK2 ELISA, for serum, plasma and cell culture supernatants,
Espèce(s)
human

Antibodies

Référence du produit
Description
Espèces réactives
Application
Monoclonal Anti-PCSK2 antibody produced in mouse, clone 3H4, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
ELISA
western blot
Anti-Prohormone Convertase PC2 Antibody, from rabbit, purified by affinity chromatography,
Espèces réactives
human, mouse, porcine, rhesus macaque
Application
immunohistochemistry
western blot
Anti-PCSK2 antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Espèces réactives
human, mouse
Application
western blot
Anti-PCSK2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunofluorescence
immunohistochemistry

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting mouse Pcsk2,
Espèce(s)
mouse
MISSION® esiRNA, targeting human PCSK2,
Espèce(s)
human