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Merck

PACRG

PARK2 co-regulated

Synonymes:
GLUP, HAK005771, PARK2CRG, RP3-495O10.2
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(135138) Summary: This gene encodes a protein that is conserved across metazoans. In vertebrates, this gene is linked in a head-to-head arrangement with the adjacent parkin gene, which is associated with autosomal recessive juvenile Parkinson's disease. These genes are co-regulated in various tissues and they share a bi-directional promoter. Both genes are associated with susceptibility to leprosy. The parkin co-regulated gene protein forms a large molecular complex with chaperones, including heat shock proteins 70 and 90, and chaperonin components. This protein is also a component of Lewy bodies in Parkinson's disease patients, and it suppresses unfolded Pael receptor-induced neuronal cell death. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(69310) PARK2 co-regulated
  • Rat(499021) Park2 co-regulated
  • domestic guinea pig(100731819) PARK2 co-regulated
  • cow(100336821) PARK2 co-regulated
  • cow(767959) PARK2 co-regulated
  • sheep(101113075) PARK2 co-regulated
  • naked mole-rat(101724544) PARK2 co-regulated
  • Zebrafish(492757) PARK2 co-regulated
  • domestic cat(101095982) PARK2 co-regulated
  • dog(484071) PARK2 co-regulated
  • chicken(421576) PARK2 co-regulated

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Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-PACRG antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Espèces réactives
human
Application
immunohistochemistry
Anti-PACRG antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human, mouse
Application
western blot
Anti-PACRG antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Espèces réactives
chicken, human, mouse
Application
immunofluorescence
immunohistochemistry

western blot

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human PACRG,
Espèce(s)
human
MISSION® esiRNA, targeting mouse Pacrg,
Espèce(s)
mouse