OTUB1
OTU domain, ubiquitin aldehyde binding 1
Synonymes:
OTB1, OTU1
Espèce(s):
Human OTUB1 (55611), Mouse Otub1 (107260), Rat Otub1 (293705), sheep OTUB1 (101122063), chicken OTUB1 (777320), domestic cat OTUB1 (101096843), cow OTUB1 (540984), dog OTUB1 (611228), domestic guinea pig Otub1 (100714472), naked mole-rat Otub1 (101706271)
ID UniProtKB:
ID du gène:
- Human(55611) Summary: The product of this gene is a member of the OTU (ovarian tumor) superfamily of predicted cysteine proteases. The encoded protein is a highly specific ubiquitin iso-peptidase, and cleaves ubiquitin from branched poly-ubiquitin chains but not from ubiquitinated substrates. It interacts with another ubiquitin protease and an E3 ubiquitin ligase that inhibits cytokine gene transcription in the immune system. It is proposed to function in specific ubiquitin-dependent pathways, possibly by providing an editing function for polyubiquitin chain growth. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008]
- Mouse(107260) OTU domain, ubiquitin aldehyde binding 1
- Rat(293705) OTU domain, ubiquitin aldehyde binding 1
- sheep(101122063) OTU domain, ubiquitin aldehyde binding 1
- chicken(777320) OTU domain, ubiquitin aldehyde binding 1
- domestic cat(101096843) OTU domain, ubiquitin aldehyde binding 1
- cow(540984) OTU domain, ubiquitin aldehyde binding 1
- dog(611228) OTU domain, ubiquitin aldehyde binding 1
- domestic guinea pig(100714472) OTU domain, ubiquitin aldehyde binding 1
- naked mole-rat(101706271) OTU domain, ubiquitin aldehyde binding 1
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Antibodies
Numéro du produit
Description
Espèces réactives
Application
Anti-OTUB1 antibody produced in rabbit, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry
western blot
western blot