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Merck

NTRK3

neurotrophic tyrosine kinase, receptor, type 3

Synonymes:
TRKC, gp145(trkC)
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(4916) Summary: This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in this gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2011]
  • Mouse(18213) neurotrophic tyrosine kinase, receptor, type 3
  • Rat(29613) neurotrophic tyrosine kinase, receptor, type 3
  • dog(609087) neurotrophic tyrosine kinase, receptor, type 3
  • cow(539126) neurotrophic tyrosine kinase, receptor, type 3
  • sheep(101121631) neurotrophic tyrosine kinase, receptor, type 3
  • domestic cat(101085548) neurotrophic tyrosine kinase, receptor, type 3
  • domestic guinea pig(100731493) neurotrophic tyrosine kinase, receptor, type 3
  • Horse(100069852) neurotrophic tyrosine kinase, receptor, type 3
  • naked mole-rat(101723255) neurotrophic tyrosine kinase, receptor, type 3
  • chicken(396081) neurotrophic tyrosine kinase, receptor, type 3

Custom & Knockdown Gene Products

ELISA

Numéro du produit
Description
Espèce(s)
Human TRKC ELISA, for serum, plasma and cell culture supernatants,
Espèce(s)
human

Antibodies

Numéro du produit
Description
Espèces réactives
Application
Anti-NTRK3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Espèces réactives
human
Application
immunofluorescence
Anti-phospho-Trk C (pTyr516) antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human, mouse, rat
Application
ELISA
immunohistochemistry

western blot
ANTI-TRKC antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
western blot
Anti-NTRK3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Espèces réactives
human
Application
immunofluorescence
ANTI-TRKC(N-TERMINAL) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Espèces réactives
human
Application
immunohistochemistry
western blot

Proteins

Numéro du produit
Description
Espèce(s)
TRKC (507-end), active, His tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Espèce(s)
human
TRKC active human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE),
Espèce(s)
human

esiRNA

Numéro du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human NTRK3 (2),
Espèce(s)
human
MISSION® esiRNA, targeting human NTRK3 (1),
Espèce(s)
human
MISSION® esiRNA, targeting mouse Ntrk3,
Espèce(s)
mouse