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Merck

MUC1

mucin 1, cell surface associated

Synonymes:
CA 15-3, CD227, EMA, H23AG, KL-6, MAM6, MCKD1, MUC-1, MUC-1/SEC, MUC-1/X, MUC1/ZD, PEM, PEMT, PUM
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(4582) Summary: This gene encodes a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. These proteins also play a role in intracellular signaling. This protein is expressed on the apical surface of epithelial cells that line the mucosal surfaces of many different tissues including lung, breast stomach and pancreas. This protein is proteolytically cleaved into alpha and beta subunits that form a heterodimeric complex. The N-terminal alpha subunit functions in cell-adhesion and the C-terminal beta subunit is involved in cell signaling. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. This gene is known to contain a highly polymorphic variable number tandem repeats (VNTR) domain. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Feb 2011]
  • Mouse(17829) mucin 1, transmembrane
  • Rat(24571) mucin 1, cell surface associated
  • dog(448784) mucin 1, cell surface associated
  • naked mole-rat(101702421) mucin 1, cell surface associated
  • domestic cat(101093832) mucin 1, cell surface associated
  • chicken(426412) mucin 1, cell surface associated
  • domestic cat(100294522) mucin 1, cell surface associated
  • cow(281333) mucin 1, cell surface associated
  • domestic guinea pig(100733534) mucin 1, cell surface associated
  • sheep(100294589) mucin 1, cell surface associated
  • sheep(101106133) mucin 1, cell surface associated
  • Domestic Rabbit(100009240) mucin 1, cell surface associated

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ELISA

Référence du produit
Description
Espèce(s)
Human Carbohydrate Antigen 15-3 / Mucin-1 ELISA Kit, for serum, plasma, cell culture supernatant and urine,
Espèce(s)
human

Antibodies

Référence du produit
Description
Espèces réactives
Application
EMA (E29) Mouse Monoclonal Antibody, ,
Espèces réactives
human
Application
immunohistochemistry
Anti-MUC1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry
MUC1 (MRQ-17) Mouse Monoclonal Antibody, ,
Espèces réactives
human
Application
immunohistochemistry
Anti-MUC1 antibody , Mouse monoclonal, clone 1D1, purified from hybridoma cell culture,
Espèces réactives
human
Application
ELISA
immunocytochemistry

immunoprecipitation (IP)

radioimmunoassay

western blot
Anti-MUC1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human MUC1,
Espèce(s)
human