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Merck

MED1

mediator complex subunit 1

Synonymes:
CRSP1, CRSP200, DRIP205, DRIP230, PBP, PPARBP, PPARGBP, RB18A, TRAP220, TRIP2
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(5469) Summary: The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. It also regulates p53-dependent apoptosis and it is essential for adipogenesis. This protein is known to have the ability to self-oligomerize. [provided by RefSeq, Jul 2008]
  • Mouse(19014) mediator complex subunit 1
  • Rat(497991) mediator complex subunit 1
  • fruit fly(40403) Mediator complex subunit 1
  • Zebrafish(571519) mediator complex subunit 1
  • cow(520734) mediator complex subunit 1
  • Horse(100054967) mediator complex subunit 1
  • sheep(101102404) mediator complex subunit 1
  • dog(480533) mediator complex subunit 1
  • domestic cat(101090305) mediator complex subunit 1
  • chicken(420004) mediator complex subunit 1
  • domestic guinea pig(100722971) mediator complex subunit 1
  • naked mole-rat(101711966) mediator complex subunit 1

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Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-MED1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Espèces réactives
human
Application
immunofluorescence
Anti-MED1 antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human, mouse
Application
ELISA
immunohistochemistry

western blot
Anti-phospho-PPAR-BP (pThr1457) antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human, mouse, rat
Application
ELISA
immunofluorescence

immunohistochemistry

western blot
Monoclonal Anti-PPARBP antibody produced in mouse, clone 2A2, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
ELISA
immunofluorescence

western blot
Monoclonal Anti-PPARBP antibody produced in mouse, clone 1G3, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
ELISA
western blot

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human MED1,
Espèce(s)
human