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Merck

LOXL2

lysyl oxidase-like 2

Synonymes:
LOR2, WS9-14
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(4017) Summary: This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. [provided by RefSeq, Jul 2008]
  • Mouse(94352) lysyl oxidase-like 2
  • Rat(290350) lysyl oxidase-like 2
  • domestic guinea pig(100729973) lysyl oxidase-like 2
  • chicken(419533) lysyl oxidase-like 2
  • domestic cat(101084102) lysyl oxidase-like 2
  • dog(486118) lysyl oxidase-like 2
  • cow(532684) lysyl oxidase-like 2
  • Domestic Rabbit(100346678) lysyl oxidase-like 2
  • sheep(101120812) lysyl oxidase-like 2
  • naked mole-rat(101700042) lysyl oxidase-like 2

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Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-LOXL2 antibody produced in rabbit, ,
Espèces réactives
human, mouse, rat
Application
immunohistochemistry
western blot
Anti-LOXL2 Antibody, clone GS341, ,
Espèces réactives
human, mouse
Application
ELISA
inhibition assay

western blot
Anti-LOXL2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Espèces réactives
human
Application
immunofluorescence
Anti-LOXL2, affinity isolated antibody,
Espèces réactives
human
Application
immunohistochemistry
Anti-LOXL2, from rabbit, purified by affinity chromatography,
Espèces réactives
bovine, human, mouse, rat
Application
immunohistochemistry
immunoprecipitation (IP)

western blot

Proteins

Référence du produit
Description
Espèce(s)
LOXL2 human, recombinant, expressed in FreeStyle 293-F cells, ≥86% (SDS-PAGE),
Espèce(s)
human
Lysyl Oxidase-like 2 (LOXL2) FLAG-tag (Sf9-derived) human, recombinant, expressed in baculovirus infected insect cells, ≥65% (SDS-PAGE),
Espèce(s)
human

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting mouse Loxl2,
Espèce(s)
mouse
MISSION® esiRNA, targeting human LOXL2,
Espèce(s)
human