LMNA
lamin A/C
Synonymes:
CDCD1, CDDC, CMD1A, CMT2B1, EMD2, FPL, FPLD, FPLD2, HGPS, IDC, LDP1, LFP, LGMD1B, LMN1, LMNC, LMNL1, PRO1
Espèce(s):
Human LMNA (4000), Mouse Lmna (16905), Rat Lmna (60374), domestic guinea pig Lmna (100735212), chicken LMNA (415464), sheep LMNA (101107924), cow LMNA (404144), domestic cat LMNA (101086199), Horse LMNA (100057663), dog LMNA (480124) ...Plus
ID UniProtKB:
ID du gène:
- Human(4000) Summary: The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Alternative splicing results in multiple transcript variants. Mutations in this gene lead to several diseases: Emery-Dreifuss muscular dystrophy, familial partial lipodystrophy, limb girdle muscular dystrophy, dilated cardiomyopathy, Charcot-Marie-Tooth disease, and Hutchinson-Gilford progeria syndrome. [provided by RefSeq, Apr 2012]
- Mouse(16905) lamin A
- Rat(60374) lamin A/C
- domestic guinea pig(100735212) lamin A/C
- chicken(415464) lamin A/C
- sheep(101107924) lamin A/C
- cow(404144) lamin A/C
- domestic cat(101086199) lamin A/C
- Horse(100057663) lamin A/C
- dog(480124) lamin A/C
- Zebrafish(195815) lamin A
- naked mole-rat(101704567) lamin A/C
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Antibodies
Référence du produit
Description
Espèces réactives
Application
Anti-Progerin Antibody, clone 13A4, clone 13A4, Upstate®, from mouse,
Espèces réactives
human
Application
ELISA
immunocytochemistry
immunoprecipitation (IP)
western blot
immunocytochemistry
immunoprecipitation (IP)
western blot
Anti-prelamin A Antibody, clone PL-1C7, clone PL-1C7, from mouse,
Espèces réactives
human, mouse
Application
ELISA
flow cytometry
immunocytochemistry
western blot
flow cytometry
immunocytochemistry
western blot
Anticorps anti-pré-lamine-A, clone 7G11, clone 7G11, from rat,
Espèces réactives
mouse
Application
immunofluorescence
western blot
western blot
Anti-Progerin antibody, Mouse monoclonal, clone 13A4, purified from hybridoma cell culture,
Espèces réactives
human
Application
immunofluorescence
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-Lamin A/C Antibody, clone 4C11, clone 4C11, from mouse,
Espèces réactives
syrian hamster, human, monkey, mouse, rat
Application
ChIP
immunofluorescence
immunoprecipitation (IP)
western blot
immunofluorescence
immunoprecipitation (IP)
western blot