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Merck

KCND2

potassium voltage-gated channel, Shal-related subfamily, member 2

Synonymes:
KV4.2, RK5
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(3751) Summary: Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shal-related subfamily, members of which form voltage-activated A-type potassium ion channels and are prominent in the repolarization phase of the action potential. This member mediates a rapidly inactivating, A-type outward potassium current which is not under the control of the N terminus as it is in Shaker channels. [provided by RefSeq, Jul 2008]
  • Mouse(16508) potassium voltage-gated channel, Shal-related family, member 2
  • Rat(65180) potassium voltage-gated channel, Shal-related subfamily, member 2
  • sheep(101122690) potassium voltage-gated channel, Shal-related subfamily, member 2
  • Domestic Rabbit(100008841) potassium voltage-gated channel, Shal-related subfamily, member 2
  • domestic guinea pig(100720728) potassium voltage-gated channel, Shal-related subfamily, member 2
  • naked mole-rat(101712898) potassium voltage-gated channel, Shal-related subfamily, member 2
  • chicken(374143) potassium voltage-gated channel, Shal-related subfamily, member 2
  • Zebrafish(570188) potassium voltage-gated channel, Shal-related subfamily, member 2
  • dog(491424) potassium voltage-gated channel, Shal-related subfamily, member 2
  • domestic cat(101093262) potassium voltage-gated channel, Shal-related subfamily, member 2
  • cow(540416) potassium voltage-gated channel, Shal-related subfamily, member 2

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Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-KCND2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry
Anti-Potassium Channel Kv4.2 Antibody, Chemicon®, from rabbit,
Espèces réactives
rat
Application
western blot
Anti-KCND2 antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
bovine, horse, human, mouse, pig, rabbit, rat
Application
western blot
Anti-Potassium Channel Kv4.2 (Shal1; RK5; Kcnd2) antibody produced in rabbit, affinity isolated antibody, lyophilized powder,
Espèces réactives
human, rat
Application
western blot

Small Molecule - Blocker

Référence du produit
Description
Espèce(s)
Guanidine hydrochloride, for molecular biology, ≥99%,
Espèce(s)
human
Guanidine hydrochloride, ≥98%,
Espèce(s)
human
Guanidine hydrochloride, organic base and chaeotropic agent, ≥99% (titration),
Espèce(s)
human
Guanidine hydrochloride, ,
Espèce(s)
human
Guanidine hydrochloride solution, Colorless liquid, 7.8 - 8.3 M, pH- 4.5 - 5.5,
Espèce(s)
human

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting mouse Kcnd2,
Espèce(s)
mouse
MISSION® esiRNA, targeting human KCND2,
Espèce(s)
human