IMPDH2
IMP (inosine 5'-monophosphate) dehydrogenase 2
Synonymes:
IMPD2, IMPDH-II
Espèce(s):
Human IMPDH2 (3615), Mouse Impdh2 (23918), Rat Impdh2 (301005), dog IMPDH2 (476630), Zebrafish impdh2 (317745), domestic guinea pig Impdh2 (100730768), naked mole-rat Impdh2 (101701391), domestic cat IMPDH2 (101080693), cow IMPDH2 (511969), sheep IMPDH2 (101107823) ...Plus
ID UniProtKB:
ID du gène:
- Human(3615) Summary: This gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation. [provided by RefSeq, Jul 2008]
- Mouse(23918) inosine 5'-phosphate dehydrogenase 2
- Rat(301005) IMP (inosine 5'-monophosphate) dehydrogenase 2
- dog(476630) IMP (inosine 5'-monophosphate) dehydrogenase 2
- Zebrafish(317745) IMP (inosine monophosphate) dehydrogenase 2
- domestic guinea pig(100730768) IMP (inosine 5'-monophosphate) dehydrogenase 2
- naked mole-rat(101701391) IMP (inosine 5'-monophosphate) dehydrogenase 2
- domestic cat(101080693) IMP (inosine 5'-monophosphate) dehydrogenase 2
- cow(511969) IMP (inosine 5'-monophosphate) dehydrogenase 2
- sheep(101107823) IMP (inosine 5'-monophosphate) dehydrogenase 2
- Domestic Rabbit(100355621) IMP (inosine 5'-monophosphate) dehydrogenase 2
- chicken(416058) IMP (inosine 5'-monophosphate) dehydrogenase 2
- Horse(100063255) IMP (inosine 5'-monophosphate) dehydrogenase 2
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Antibodies
Référence du produit
Description
Espèces réactives
Application
Anti-IMPDH2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-IMPDH2 Mouse mAb (1E12-B6), liquid, clone 1E12-B6, Calbiochem®,
Espèces réactives
human
Application
Monoclonal Anti-IMPDH2 antibody produced in mouse, clone 1E12-B6, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
ELISA
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-IMPDH2 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
immunofluorescence
western blot
western blot
Anti-IMPDH2 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
western blot
Small Molecule - Inhibitor
Référence du produit
Description
Espèce(s)
Proteins
Référence du produit
Description
Espèce(s)
Inosine Monophosphate Dehydrogenase Type II human, recombinant, expressed in E. coli,
Espèce(s)
human