Accéder au contenu
Merck

IL12A

interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)

Synonymes:
CLMF, IL-12A, NFSK, NKSF1, P35
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(3592) Summary: This gene encodes a subunit of a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. The cytokine is a disulfide-linked heterodimer composed of the 35-kD subunit encoded by this gene, and a 40-kD subunit that is a member of the cytokine receptor family. This cytokine is required for the T-cell-independent induction of interferon (IFN)-gamma, and is important for the differentiation of both Th1 and Th2 cells. The responses of lymphocytes to this cytokine are mediated by the activator of transcription protein STAT4. Nitric oxide synthase 2A (NOS2A/NOS2) is found to be required for the signaling process of this cytokine in innate immunity. [provided by RefSeq, Jul 2008]
  • Mouse(16159) interleukin 12a
  • Rat(84405) interleukin 12A
  • domestic guinea pig(100379543) interleukin 12a
  • chicken(407090) interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)
  • Zebrafish(445410) interleukin 12a
  • Horse(100034215) interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)
  • domestic cat(493741) interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)
  • dog(403977) interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)
  • cow(281856) interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)
  • Goat(100861293) interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)
  • sheep(443064) interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)
  • naked mole-rat(101701392) interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)

Custom & Knockdown Gene Products

ELISA

Numéro du produit
Description
Espèce(s)
Human IL-12 p70 ELISA Kit, for serum, plasma, cell culture supernatant and urine,
Espèce(s)
human
Mouse IL-12 P40/70 ELISA Kit, for serum, plasma and cell culture supernatant,
Espèce(s)
mouse
Rhesus Macaque IL12A / IL12B ELISA Kit, ,
Espèce(s)
Porcine IL12A / IL12B ELISA Kit, ,
Espèce(s)

Antibodies

Numéro du produit
Description
Espèces réactives
Application
Anti-Interleukin-12 antibody produced in goat, IgG fraction of antiserum,
Espèces réactives
mouse
Application
neutralization
western blot
Anti-IL-12A Antibody, clone 1G10 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Espèces réactives
baboon, bovine, canine, feline, goat, human, monkey, mouse, porcine, sheep
Application
affinity binding assay
flow cytometry

western blot
Anti-Interleukin-12 antibody produced in goat, IgG fraction of antiserum, lyophilized powder,
Espèces réactives
human
Application
neutralization

Proteins

Numéro du produit
Description
Espèce(s)
IL-12 human, recombinant, expressed in CHO cells, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture,
Espèce(s)
human
IL-35 (mouse): FC (human), recombinant, expressed in CHO cells,
Espèce(s)
mouse
Interleukin-12 human, ≥97% (SDS-PAGE and N-terminal analysis), recombinant, expressed in baculovirus infected Sf21 cells, lyophilized powder, suitable for cell culture,
Espèce(s)
human
Interleukin-12 from mouse, ≥97% (SDS-PAGE), recombinant, expressed in baculovirus infected Sf21 cells, lyophilized powder, suitable for cell culture,
Espèce(s)
mouse

esiRNA

Numéro du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human IL12A,
Espèce(s)
human
MISSION® esiRNA, targeting mouse Il12a,
Espèce(s)
mouse