GLE1
GLE1 RNA export mediator
Synonymes:
GLE1L, LCCS, LCCS1, hGLE1
Espèce(s):
Human GLE1 (2733), Mouse Gle1 (74412), Rat Gle1 (362098), sheep GLE1 (101119123), Horse GLE1 (100066964), domestic guinea pig Gle1 (100732111), naked mole-rat Gle1 (101722063), cow GLE1 (540982), chicken GLE1 (417212), Zebrafish gle1 (445408) ...Plus
ID UniProtKB:
ID du gène:
- Human(2733) Summary: This gene encodes a predicted 75-kDa polypeptide with high sequence and structure homology to yeast Gle1p, which is nuclear protein with a leucine-rich nuclear export sequence essential for poly(A)+RNA export. Inhibition of human GLE1L by microinjection of antibodies against GLE1L in HeLa cells resulted in inhibition of poly(A)+RNA export. Immunoflourescence studies show that GLE1L is localized at the nuclear pore complexes. This localization suggests that GLE1L may act at a terminal step in the export of mature RNA messages to the cytoplasm. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(74412) GLE1 RNA export mediator (yeast)
- Rat(362098) GLE1 RNA export mediator
- sheep(101119123) GLE1 RNA export mediator homolog (yeast)
- Horse(100066964) GLE1 RNA export mediator homolog (yeast)
- domestic guinea pig(100732111) GLE1 RNA export mediator
- naked mole-rat(101722063) GLE1 RNA export mediator homolog (yeast)
- cow(540982) GLE1 RNA export mediator homolog (yeast)
- chicken(417212) GLE1 RNA export mediator
- Zebrafish(445408) GLE1 RNA export mediator homolog (yeast)
- dog(480704) GLE1 RNA export mediator homolog (yeast)
- domestic cat(101080492) GLE1 RNA export mediator homolog (yeast)
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Référence du produit
Description
Espèces réactives
Application
Anti-GLE1L antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
western blot
Anti-GLE1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry
western blot
western blot
Anti-GLE1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Espèces réactives
human
Application
immunofluorescence
Anti-GLE1 antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
horse, human, rat
Application
western blot
Monoclonal Anti-GLE1 antibody produced in mouse, clone 1D8, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
ELISA
immunofluorescence
western blot
immunofluorescence
western blot