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Merck

GCLM

glutamate-cysteine ligase, modifier subunit

Synonymes:
GLCLR
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(2730) Summary: Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase, is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. Gamma glutamylcysteine synthetase deficiency has been implicated in some forms of hemolytic anemia. [provided by RefSeq, Jul 2008]
  • Mouse(14630) glutamate-cysteine ligase, modifier subunit
  • Rat(29739) glutamate cysteine ligase, modifier subunit
  • dog(612283) glutamate-cysteine ligase, modifier subunit
  • domestic guinea pig(100725164) glutamate-cysteine ligase, modifier subunit
  • domestic cat(101081562) glutamate-cysteine ligase, modifier subunit
  • fruit fly(248194) Glutamate-cysteine ligase modifier subunit
  • chicken(424492) glutamate-cysteine ligase, modifier subunit
  • naked mole-rat(101703324) glutamate-cysteine ligase, modifier subunit
  • sheep(101117899) glutamate-cysteine ligase, modifier subunit
  • Zebrafish(333974) glutamate-cysteine ligase, modifier subunit
  • cow(525659) glutamate-cysteine ligase, modifier subunit

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Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-GCLM Antibody, clone 1D19 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Espèces réactives
human, monkey, mouse
Application
affinity binding assay
flow cytometry

immunocytochemistry

immunohistochemistry

western blot
Anti-GCLM antibody produced in rabbit, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunofluorescence
immunohistochemistry

western blot
Anti-GCLM antibody produced in rabbit, ,
Espèces réactives
Application
western blot
Anti-GCLM antibody produced in rabbit, ,
Espèces réactives
human, mouse
Application
immunohistochemistry
western blot
Anti-GCLM antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
western blot

Small Molecule - Inhibitor

Référence du produit
Description
Espèce(s)
L-Buthionine-sulfoximine, ≥97% (TLC),
Espèce(s)
human

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human GCLM,
Espèce(s)
human
MISSION® esiRNA, targeting mouse Gclm,
Espèce(s)
mouse