FGF8
fibroblast growth factor 8 (androgen-induced)
Synonymes:
AIGF, FGF-8, HBGF-8, HH6, KAL6
Espèce(s):
Human FGF8 (2253), Mouse Fgf8 (14179), Rat Fgf8 (29349), chicken FGF8 (396313), domestic cat FGF8 (101084652), dog FGF8 (403868), sheep FGF8 (101113716), cow FGF8 (326284), Domestic Rabbit FGF8 (100008834), naked mole-rat Fgf8 (101699438)
ID UniProtKB:
ID du gène:
- Human(2253) Summary: The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein is known to be a factor that supports androgen and anchorage independent growth of mammary tumor cells. Overexpression of this gene has been shown to increase tumor growth and angiogensis. The adult expression of this gene is restricted to testes and ovaries. Temporal and spatial pattern of this gene expression suggests its function as an embryonic epithelial factor. Studies of the mouse and chick homologs revealed roles in midbrain and limb development, organogenesis, embryo gastrulation and left-right axis determination. The alternative splicing of this gene results in four transcript variants. [provided by RefSeq, Jul 2008]
- Mouse(14179) fibroblast growth factor 8
- Rat(29349) fibroblast growth factor 8
- chicken(396313) fibroblast growth factor 8 (androgen-induced)
- domestic cat(101084652) fibroblast growth factor 8 (androgen-induced)
- dog(403868) fibroblast growth factor 8 (androgen-induced)
- sheep(101113716) fibroblast growth factor 8 (androgen-induced)
- cow(326284) fibroblast growth factor 8 (androgen-induced)
- Domestic Rabbit(100008834) fibroblast growth factor 8 (androgen-induced)
- naked mole-rat(101699438) fibroblast growth factor 8 (androgen-induced)
- domestic guinea pig(100721355) fibroblast growth factor 8 (androgen-induced)
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Antibodies
Référence du produit
Description
Espèces réactives
Application
Monoclonal Anti-FGF8 antibody produced in mouse, clone 3H2, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
ELISA
western blot
western blot
Anti-FGF8 Mouse mAb (2A10), liquid, clone 2A10, Calbiochem®,
Espèces réactives
human, mouse, rat
Application
Monoclonal Anti-FGF8 antibody produced in mouse, clone 2A11, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
ELISA
proximity ligation assay
proximity ligation assay
Proteins
Référence du produit
Description
Espèce(s)
Fibroblast Growth Factor-8b from mouse, >97% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder,
Espèce(s)
mouse
esiRNA
Référence du produit
Description
Espèce(s)