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Merck

ENPP1

ectonucleotide pyrophosphatase/phosphodiesterase 1

Synonymes:
ARHR2, M6S1, NPP1, NPPS, PC-1, PCA1, PDNP1
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(5167) Summary: This gene is a member of the ecto-nucleotide pyrophosphatase/phosphodiesterase (ENPP) family. The encoded protein is a type II transmembrane glycoprotein comprising two identical disulfide-bonded subunits. This protein has broad specificity and cleaves a variety of substrates, including phosphodiester bonds of nucleotides and nucleotide sugars and pyrophosphate bonds of nucleotides and nucleotide sugars. This protein may function to hydrolyze nucleoside 5' triphosphates to their corresponding monophosphates and may also hydrolyze diadenosine polyphosphates. Mutations in this gene have been associated with 'idiopathic' infantile arterial calcification, ossification of the posterior longitudinal ligament of the spine (OPLL), and insulin resistance. [provided by RefSeq, Jul 2008]
  • Mouse(18605) ectonucleotide pyrophosphatase/phosphodiesterase 1
  • Rat(85496) ectonucleotide pyrophosphatase/phosphodiesterase 1
  • domestic cat(101094350) ectonucleotide pyrophosphatase/phosphodiesterase 1
  • sheep(101123048) ectonucleotide pyrophosphatase/phosphodiesterase 1
  • chicken(426929) ectonucleotide pyrophosphatase/phosphodiesterase 1
  • Domestic Rabbit(100009517) ectonucleotide pyrophosphatase/phosphodiesterase 1
  • cow(615535) ectonucleotide pyrophosphatase/phosphodiesterase 1
  • Horse(100073097) ectonucleotide pyrophosphatase/phosphodiesterase 1
  • domestic guinea pig(100726931) ectonucleotide pyrophosphatase/phosphodiesterase 1
  • naked mole-rat(101706464) ectonucleotide pyrophosphatase/phosphodiesterase 1
  • Zebrafish(562399) ectonucleotide pyrophosphatase/phosphodiesterase 1
  • dog(476153) ectonucleotide pyrophosphatase/phosphodiesterase 1

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Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-ENPP1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry
Anti-ENPP1 antibody produced in mouse, IgG fraction of antiserum, buffered aqueous solution,
Espèces réactives
human
Application
western blot

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human ENPP1,
Espèce(s)
human
MISSION® esiRNA, targeting mouse Enpp1,
Espèce(s)
mouse
MISSION® esiRNA, targeting mouse Enpp1,
Espèce(s)
mouse