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Merck

DPYD

dihydropyrimidine dehydrogenase

Synonymes:
DHP, DHPDHASE, DPD
Espèce(s):
Human DPYD (1806), Mouse Dpyd (99586), Rat Dpyd (81656), domestic guinea pig Dpyd (100727906), chicken DPYD (429083), sheep DPYD (101109311), Horse DPYD (100057177), naked mole-rat Dpyd (101704452), domestic cat DPYD (101084380), dog DPYD (479935)
ID UniProtKB:
Q12882, A2RRQ2, A2RRQ3, A8K5A2, A8MWG9, B1AN21, E9PFN1, Q16694
ID du gène:
  • Human(1806) Summary: The protein encoded by this gene is a pyrimidine catabolic enzyme and the initial and rate-limiting factor in the pathway of uracil and thymidine catabolism. Mutations in this gene result in dihydropyrimidine dehydrogenase deficiency, an error in pyrimidine metabolism associated with thymine-uraciluria and an increased risk of toxicity in cancer patients receiving 5-fluorouracil chemotherapy. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]
  • Mouse(99586) dihydropyrimidine dehydrogenase
  • Rat(81656) dihydropyrimidine dehydrogenase
  • domestic guinea pig(100727906) dihydropyrimidine dehydrogenase
  • chicken(429083) dihydropyrimidine dehydrogenase
  • sheep(101109311) dihydropyrimidine dehydrogenase
  • Horse(100057177) dihydropyrimidine dehydrogenase
  • naked mole-rat(101704452) dihydropyrimidine dehydrogenase
  • domestic cat(101084380) dihydropyrimidine dehydrogenase
  • dog(479935) dihydropyrimidine dehydrogenase
  • cow(281124) dihydropyrimidine dehydrogenase

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Antibodies

Référence du produit
Description
Espèces réactives
Application
ABC451
Anti-Dihydropyrimidine dehydrogenase/DPYD Antibody, from rabbit, purified by affinity chromatography,
Espèces réactives
bovine, horse, human, porcine, primate
Application
immunohistochemistry
western blot
SAB4300722
Anti-DPYD antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human, mouse, rat
Application
immunohistochemistry
western blot
ST1672
Anti-DPYD Mouse mAb (7D4), liquid, clone 7D4, Calbiochem®,
Espèces réactives
human
Application

esiRNA

Référence du produit
Description
Espèce(s)
EHU060711
MISSION® esiRNA, targeting human DPYD,
Espèce(s)
human