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Merck

DNMT3A

DNA (cytosine-5-)-methyltransferase 3 alpha

Synonymes:
DNMT3A2, M.HsaIIIA
Espèce(s):
Human DNMT3A (1788), Mouse Dnmt3a (13435), Rat Dnmt3a (444984), sheep DNMT3A (100500776), Domestic Rabbit DNMT3A (100344715), cow DNMT3A (359716), domestic cat DNMT3A (100510798), Horse DNMT3A (100055881), dog DNMT3A (482996), naked mole-rat Dnmt3a (101718745) ...Plus
ID UniProtKB:
Q9Y6K1, E9PEB8, Q86TE8, Q86XF5, Q8IZV0, Q8WXU9
ID du gène:
  • Human(1788) Summary: CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
  • Mouse(13435) DNA methyltransferase 3A
  • Rat(444984) DNA (cytosine-5-)-methyltransferase 3 alpha
  • sheep(100500776) DNA (cytosine-5-)-methyltransferase 3 alpha
  • Domestic Rabbit(100344715) DNA (cytosine-5-)-methyltransferase 3 alpha
  • cow(359716) DNA (cytosine-5-)-methyltransferase 3 alpha
  • domestic cat(100510798) DNA (cytosine-5-)-methyltransferase 3 alpha
  • Horse(100055881) DNA (cytosine-5-)-methyltransferase 3 alpha
  • dog(482996) DNA (cytosine-5-)-methyltransferase 3 alpha
  • naked mole-rat(101718745) DNA (cytosine-5-)-methyltransferase 3 alpha
  • domestic guinea pig(100721625) DNA (cytosine-5-)-methyltransferase 3 alpha
  • chicken(421991) DNA (cytosine-5-)-methyltransferase 3 alpha

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Antibodies

Numéro du produit
Description
Espèces réactives
Application
SAB6012218
Anti DNA methyltransferase 3 alpha Antibody, clone 23GB2230, Rabbit Monoclonal, clone 23GB2230, recombinant rabbit monoclonal, expressed in HEK293 cells,
Espèces réactives
human, rat
Application
flow cytometry
western blot
HPA026588
Anti-DNMT3A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human, mouse, rat
Application
immunofluorescence
immunohistochemistry
07-2050
Anti-DNMT3A2 Antibody, from rabbit,
Espèces réactives
human
Application
ELISA
immunocytochemistry
western blot
SAB5701326
Anti- DNMT3A antibody produced in rabbit, ,
Espèces réactives
human, mouse, rat
Application
immunohistochemistry
western blot
SAB5700766
Anti-DNMT3A antibody produced in rabbit, ,
Espèces réactives
human, mouse, rat
Application
immunofluorescence
western blot

Small Molecule - Inhibitor

Numéro du produit
Description
Espèce(s)
A3656
5-Aza-2′-deoxycytidine, ≥97%,
Espèce(s)
human
A1287
5-Azacytidine, Hybri-Max™, γ-irradiated, lyophilized powder, BioXtra, suitable for hybridoma,
Espèce(s)
human
1045520
Azacitidine, United States Pharmacopeia (USP) Reference Standard,
Espèce(s)
human
PHR1911
Azacitidine, Pharmaceutical Secondary Standard; Certified Reference Material,
Espèce(s)
human
A2385
5-Azacytidine, ≥98% (HPLC),
Espèce(s)
human

Proteins

Numéro du produit
Description
Espèce(s)
SRP0128
DNMT3a Active human, recombinant, expressed in baculovirus infected insect cells,
Espèce(s)
human
SRP0396
DNMT3A/DNMT3L active human, recombinant, expressed in baculovirus infected Sf9 cells, ≥90% (SDS-PAGE),
Espèce(s)
human

esiRNA

Numéro du produit
Description
Espèce(s)
EHU123831
MISSION® esiRNA, targeting human DNMT3A,
Espèce(s)
human
EMU028371
MISSION® esiRNA, targeting mouse Dnmt3a,
Espèce(s)
mouse