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Merck

DHCR24

24-dehydrocholesterol reductase

Synonymes:
DCE, Nbla03646, SELADIN1, seladin-1
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(1718) Summary: This gene encodes a flavin adenine dinucleotide (FAD)-dependent oxidoreductase which catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis. The protein contains a leader sequence that directs it to the endoplasmic reticulum membrane. Missense mutations in this gene have been associated with desmosterolosis. Also, reduced expression of the gene occurs in the temporal cortex of Alzheimer disease patients and overexpression has been observed in adrenal gland cancer cells. [provided by RefSeq, Jul 2008]
  • Mouse(74754) 24-dehydrocholesterol reductase
  • Rat(298298) 24-dehydrocholesterol reductase
  • domestic guinea pig(100714000) 24-dehydrocholesterol reductase
  • naked mole-rat(101703975) 24-dehydrocholesterol reductase
  • dog(489573) 24-dehydrocholesterol reductase
  • domestic cat(101098730) 24-dehydrocholesterol reductase
  • Horse(100034055) 24-dehydrocholesterol reductase
  • cow(533726) 24-dehydrocholesterol reductase
  • sheep(101123162) 24-dehydrocholesterol reductase
  • Zebrafish(494102) 24-dehydrocholesterol reductase
  • chicken(424661) 24-dehydrocholesterol reductase

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Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-DHCR24 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Espèces réactives
human
Application
immunohistochemistry
Anti-DHCR24 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry
western blot
Anti-DHCR24 antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
bovine, dog, guinea pig, horse, human, mouse, rat
Application
immunohistochemistry
western blot
Anti-DHCR24 antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
bovine, human, mouse, rabbit, rat
Application
western blot

Small Molecule - Inhibitor

Référence du produit
Description
Espèce(s)
Triparanol, ≥97% (HPLC), powder,
Espèce(s)
human

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting mouse Dhcr24,
Espèce(s)
mouse
MISSION® esiRNA, targeting human DHCR24,
Espèce(s)
human