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Merck

CAPN6

calpain 6

Synonymes:
CANPX, CAPNX, CalpM, DJ914P14.1
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(827) Summary: Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large subunit possesses a cysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. The protein encoded by this gene is highly expressed in the placenta. Its C-terminal region lacks any homology to the calmodulin-like domain of other calpains. The protein lacks critical active site residues and thus is suggested to be proteolytically inactive. The protein may play a role in tumor formation by inhibiting apoptosis and promoting angiogenesis. [provided by RefSeq, Nov 2009]
  • Mouse(12338) calpain 6
  • Rat(83685) calpain 6
  • dog(492068) calpain 6
  • chicken(422341) calpain 6
  • naked mole-rat(101712448) calpain 6
  • domestic guinea pig(100720507) calpain 6
  • sheep(101110122) calpain 6
  • Domestic Rabbit(100348781) calpain 6
  • domestic cat(101095474) calpain 6
  • Horse(100054264) calpain 6
  • cow(539360) calpain 6

Custom & Knockdown Gene Products

Antibodies

Numéro du produit
Description
Espèces réactives
Application
Anti-CAPN6 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry
western blot
Anti-CAPN6 antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
Application
immunofluorescence
immunohistochemistry

western blot

esiRNA

Numéro du produit
Description
Espèce(s)
MISSION® esiRNA, targeting mouse Capn6,
Espèce(s)
mouse
MISSION® esiRNA, targeting human CAPN6,
Espèce(s)
human