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Merck

BMPR2

bone morphogenetic protein receptor, type II (serine/threonine kinase)

Synonymes:
BMPR-II, BMPR3, BMR2, BRK-3, PPH1, T-ALK
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(659) Summary: This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of two different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension, both familial and fenfluramine-associated, and with pulmonary venoocclusive disease. [provided by RefSeq, Jul 2008]
  • Mouse(12168) bone morphogenetic protein receptor, type II (serine/threonine kinase)
  • Rat(140590) bone morphogenetic protein receptor, type II (serine/threonine kinase)
  • cow(407127) bone morphogenetic protein receptor, type II (serine/threonine kinase)
  • naked mole-rat(101701138) bone morphogenetic protein receptor, type II (serine/threonine kinase)
  • Domestic Rabbit(100350246) bone morphogenetic protein receptor, type II (serine/threonine kinase)
  • sheep(101103793) bone morphogenetic protein receptor, type II (serine/threonine kinase)
  • domestic guinea pig(100736232) bone morphogenetic protein receptor, type II (serine/threonine kinase)
  • chicken(374147) bone morphogenetic protein receptor, type II (serine/threonine kinase)
  • sheep(100294556) bone morphogenetic protein receptor, type II (serine/threonine kinase)
  • domestic cat(101096338) bone morphogenetic protein receptor, type II (serine/threonine kinase)
  • dog(478875) bone morphogenetic protein receptor, type II (serine/threonine kinase)

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ELISA

Référence du produit
Description
Espèce(s)
Human BMPR-II ELISA Kit, for cell culture supernatants, plasma, and serum samples,
Espèce(s)
human

Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-BMPR2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry
Monoclonal Anti-BMPR2 antibody produced in mouse, clone 3F6, ascites fluid,
Espèces réactives
human, monkey, mouse, rat
Application
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-BMPR2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Espèces réactives
human
Application
immunofluorescence
Anti-BMR2 Antibody, clone 3F6, ascites fluid, clone 3F6, from mouse,
Espèces réactives
human, monkey, mouse, rat
Application
immunofluorescence
immunohistochemistry

western blot
Anti-BMPR-II Antibody, clone 9F4.1, clone 9F4.1, from mouse,
Espèces réactives
human
Application
immunohistochemistry
western blot

Proteins

Référence du produit
Description
Espèce(s)
BMPR2 (174-end), active, His tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Espèce(s)
human

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human BMPR2,
Espèce(s)
human
MISSION® esiRNA, targeting mouse Bmpr2,
Espèce(s)
mouse