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Merck

ARID1A

AT rich interactive domain 1A (SWI-like)

Synonymes:
B120, BAF250, BAF250a, BM029, C1orf4, ELD, MRD14, OSA1, P270, SMARCF1, hELD, hOSA1
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(8289) Summary: This gene encodes a member of the SWI/SNF family, whose members have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. It possesses at least two conserved domains that could be important for its function. First, it has a DNA-binding domain that can specifically bind an AT-rich DNA sequence known to be recognized by a SNF/SWI complex at the beta-globin locus. Second, the C-terminus of the protein can stimulate glucocorticoid receptor-dependent transcriptional activation. It is thought that the protein encoded by this gene confers specificity to the SNF/SWI complex and may recruit the complex to its targets through either protein-DNA or protein-protein interactions. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(93760) AT rich interactive domain 1A (SWI-like)
  • Rat(297867) AT rich interactive domain 1A (SWI-like)
  • sheep(101115263) AT rich interactive domain 1A (SWI-like)
  • cow(540181) AT rich interactive domain 1A (SWI-like)
  • domestic cat(101086737) AT rich interactive domain 1A (SWI-like)
  • naked mole-rat(101715459) AT rich interactive domain 1A (SWI-like)
  • dog(487352) AT rich interactive domain 1A (SWI-like)
  • domestic guinea pig(100714305) AT rich interactive domain 1A (SWI-like)
  • chicken(419542) AT rich interactive domain 1A (SWI-like)

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Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-ARID1A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunofluorescence
immunohistochemistry

western blot
Monoclonal Anti-ARID1A antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL3595, purified immunoglobulin, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunofluorescence
immunohistochemistry

western blot
Anti-BAF250a/ARID1a Antibody, clone PSG3, clone PSG3, Upstate®, from mouse,
Espèces réactives
human
Application
immunofluorescence
western blot
Anti-ARID1A antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human, mouse
Application
western blot
Monoclonal Anti-ARID1A antibody produced in mouse, clone GT3611, affinity isolated antibody,
Espèces réactives
human, mouse
Application
immunofluorescence
immunohistochemistry

western blot

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting mouse Arid1a,
Espèce(s)
mouse
MISSION® esiRNA, targeting human ARID1A,
Espèce(s)
human