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Merck

ALDOA

aldolase A, fructose-bisphosphate

Synonymes:
ALDA, GSD12
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(226) Summary: The protein encoded by this gene, Aldolase A (fructose-bisphosphate aldolase), is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Three aldolase isozymes (A, B, and C), encoded by three different genes, are differentially expressed during development. Aldolase A is found in the developing embryo and is produced in even greater amounts in adult muscle. Aldolase A expression is repressed in adult liver, kidney and intestine and similar to aldolase C levels in brain and other nervous tissue. Aldolase A deficiency has been associated with myopathy and hemolytic anemia. Alternative splicing and alternative promoter usage results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 3 and 10. [provided by RefSeq, Aug 2011]
  • Mouse(11674) aldolase A, fructose-bisphosphate
  • Rat(24189) aldolase A, fructose-bisphosphate
  • domestic cat(101100776) aldolase A, fructose-bisphosphate
  • chicken(396078) aldolase A, fructose-bisphosphate
  • sheep(443085) aldolase A, fructose-bisphosphate
  • naked mole-rat(101702582) aldolase A, fructose-bisphosphate
  • Domestic Rabbit(100009055) aldolase A, fructose-bisphosphate
  • Horse(100066121) aldolase A, fructose-bisphosphate
  • dog(479787) aldolase A, fructose-bisphosphate
  • cow(509566) aldolase A, fructose-bisphosphate
  • domestic guinea pig(100730400) aldolase A, fructose-bisphosphate

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Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-ALDOA antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunofluorescence
immunohistochemistry

western blot
ANTI-ALDOLASE (ALDOA)(N-TERMINAL) antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
immunofluorescence
immunohistochemistry

western blot
Monoclonal Anti-ALDOA antibody produced in mouse, clone 3D9-6F3, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human, mouse, rat
Application
ELISA
immunofluorescence

western blot
Anti-ALDOA antibody produced in rabbit, ,
Espèces réactives
human, mouse, rat
Application
immunohistochemistry
western blot
Anti-ALDOA antibody produced in rabbit, IgG fraction of antiserum,
Espèces réactives
dog, human, rabbit
Application
western blot

Proteins

Référence du produit
Description
Espèce(s)
Aldolase A human, recombinant, expressed in E. coli, ≥95% (SDS-PAGE),
Espèce(s)
human

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human ALDOA,
Espèce(s)
human
MISSION® esiRNA, targeting mouse Aldoa,
Espèce(s)
mouse