- Antibacterial strategies from the sea: polymer-bound cl-catechols for prevention of biofilm formation.
Antibacterial strategies from the sea: polymer-bound cl-catechols for prevention of biofilm formation.
Advanced materials (Deerfield Beach, Fla.) (2012-11-10)
Luis García-Fernández, Jiaxi Cui, Cristina Serrano, Zahid Shafiq, Radu A Gropeanu, Verónica San Miguel, Jagoba Iturri Ramos, Miao Wang, Gunther K Auernhammer, Sandra Ritz, Ali A Golriz, Rüdiger Berger, Manfred Wagner, Aránzazu del Campo
PMID23139083
ABSTRACT
Inspired by the amino acid 2-chloro-4,5-dihydroxyphenylalanine (Cl-DOPA), present in the composition of the proteinaceous glue of the sandcastle worm Phragmatopoma californica, a simple strategy is presented to confer antifouling properties to polymer surfaces using (but not releasing) a bioinspired biocide. Cl-Dopamine is used to functionalize polymer materials and hydrogel films easily, to prevent biofilm formation on them.
MATERIALS