SML2602
CW3388
≥98% (HPLC)
Synonym(s):
1-([1,1′-Biphenyl]-4-ylmethyl)octahydro-azocine
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About This Item
Assay
≥98% (HPLC)
form
oil
color
colorless to yellow
storage temp.
2-8°C
Biochem/physiol Actions
CW3388 is a cell active and highly potent enhancer of oligodendrocyte formation. CW3388 potently inhibits the cholesterol biosynthesis enzyme Δ8,7-sterol isomerase (EBP). It promotes myelination in vitro.
Storage Class Code
13 - Non Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
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Cell chemical biology, 26(4), 593-599 (2019-02-19)
Small molecules that promote oligodendrocyte formation have been identified in "drug repurposing" screens to nominate candidate therapeutics for diseases in which myelin is lost, including multiple sclerosis. We recently reported that many such molecules enhance oligodendrocyte formation not by their
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