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Merck

PFKL

phosphofructokinase, liver

Synonyms:
PFK-B
Species:
UniProtKB ID:
Gene ID:
  • Human(5211) Summary: Phosphofructokinase (PFK) is a tetrameric enzyme that catalyzes a key step in glycolysis, namely the conversion of D-fructose 6-phosphate to D-fructose 1,6-bisphosphate. Separate genes encode a muscle subunit (M) and a liver subunit (L). PFK from muscle is a homotetramer of M subunits, PFK from liver is a homotetramer of L-subunits, while PFK from platelets can be composed of any tetrameric combination of M and L subunits. The protein encoded by this gene represents the L subunit. Alternate splicing results in two transcript variants, one of which is a candidate for nonsense-mediated decay (NMD). [provided by RefSeq, Aug 2008]
  • Mouse(18641) phosphofructokinase, liver, B-type
  • Rat(25741) phosphofructokinase, liver
  • dog(487797) phosphofructokinase, liver
  • chicken(769850) phosphofructokinase, liver
  • domestic guinea pig(100720033) phosphofructokinase, liver
  • domestic cat(101090792) phosphofructokinase, liver
  • cow(508683) phosphofructokinase, liver
  • naked mole-rat(101724978) phosphofructokinase, liver

Custom & Knockdown Gene Products

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-PFKL antibody produced in rabbit, IgG fraction of antiserum,
Species Reactivity
bovine, dog, guinea pig, horse, human, mouse, rat
Application
western blot
Monoclonal Anti-PFKL antibody produced in mouse, clone 2A9, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
ELISA
western blot

Kits

Product Number
Description
Species
Phosphofructokinase (PFK) Activity Colorimetric Assay Kit, sufficient for 100 colorimetric tests,
Species
mouse, rat, human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human PFKL,
Species
human
MISSION® esiRNA, targeting mouse Pfkl,
Species
mouse