CRK
v-crk avian sarcoma virus CT10 oncogene homolog
Synonyms:
CRKII, p38
Species:
Human CRK (1398), Mouse Crk (12928), Rat Crk (54245), Thale Cress CRK (824217), Thale Cress CRK (828087), fruit fly Crk (43775), fruit fly crk (248187), Zebrafish crk (445234), chicken CRK (417553), dog CRK (100684309) ...More
UniProtKB ID:
Gene ID:
- Human(1398) Summary: This gene encodes a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. The product of this gene has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction. The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation. Two alternative transcripts encoding different isoforms with distinct biological activity have been described. [provided by RefSeq, Jul 2008]
- Mouse(12928) v-crk sarcoma virus CT10 oncogene homolog (avian)
- Rat(54245) v-crk avian sarcoma virus CT10 oncogene homolog
- Thale Cress(824217) CDPK-related kinase
- Thale Cress(828087) actin related protein 2/3 complex, subunit 5
- fruit fly(43775) CG1587 gene product from transcript CG1587-RD
- fruit fly(248187) crooked setae
- Zebrafish(445234) v-crk sarcoma virus CT10 oncogene homolog (avian)
- chicken(417553) v-crk sarcoma virus CT10 oncogene homolog
- dog(100684309) v-crk sarcoma virus CT10 oncogene homolog (avian)
- domestic cat(101086100) v-crk sarcoma virus CT10 oncogene homolog (avian)
- cow(512841) v-crk sarcoma virus CT10 oncogene homolog (avian)
- sheep(101115380) v-crk sarcoma virus CT10 oncogene homolog (avian)
- domestic guinea pig(100718486) v-crk sarcoma virus CT10 oncogene homolog (avian)
- naked mole-rat(101717585) v-crk sarcoma virus CT10 oncogene homolog (avian)
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-CRK antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
proximity ligation assay
western blot
western blot
Anti-CRK/CRKII Antibody, clone 4Y2C2, Rabbit Monoclonal, ,
Species Reactivity
mouse
Application
western blot
Anti-Phospho-CRK-Y221 antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
western blot
Anti-CRK antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
Anti-Phospho-CRK/CRKII-Y221 antibody produced in rabbit, ,
Species Reactivity
human, rat
Application
western blot