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Merck

CLPS

colipase, pancreatic

Synonyms:
Species:
UniProtKB ID:
Gene ID:
  • Human(1208) Summary: The protein encoded by this gene is a cofactor needed by pancreatic lipase for efficient dietary lipid hydrolysis. It binds to the C-terminal, non-catalytic domain of lipase, thereby stabilizing an active conformation and considerably increasing the overall hydrophobic binding site. The gene product allows lipase to anchor noncovalently to the surface of lipid micelles, counteracting the destabilizing influence of intestinal bile salts. This cofactor is only expressed in pancreatic acinar cells, suggesting regulation of expression by tissue-specific elements. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]
  • Mouse(109791) colipase, pancreatic
  • Rat(25680) colipase, pancreatic
  • cow(525923) colipase, pancreatic
  • Horse(100053646) colipase, pancreatic
  • domestic cat(101100391) colipase, pancreatic
  • Domestic Rabbit(100009061) colipase, pancreatic
  • sheep(101119081) colipase, pancreatic
  • dog(403970) colipase, pancreatic
  • naked mole-rat(101718096) colipase, pancreatic
  • chicken(771102) colipase, pancreatic
  • domestic guinea pig(100723751) colipase, pancreatic

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-CLPS antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-CLPS antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-Colipase Antibody, serum, from rabbit,
Species Reactivity
mouse
Application
western blot
Monoclonal Anti-CLPS, (C-terminal) antibody produced in mouse, clone 4G3, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
Monoclonal Anti-CLPS antibody produced in mouse, clone 1G5, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA

Proteins

Product Number
Description
Species
Colipase from porcine pancreas, essentially salt-free, lyophilized powder,
Species

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human CLPS,
Species
human
MISSION® esiRNA, targeting mouse Clps,
Species
mouse