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Merck

ADRA1B

adrenoceptor alpha 1B

Synonyms:
ADRA1, ALPHA1BAR
Species:
Human ADRA1B (147), Mouse Adra1b (11548), Rat Adra1b (24173), domestic guinea pig Adra1b (100735480), domestic cat ADRA1B (101092238), dog ADRA1B (403962), chicken ADRA1B (373890), Domestic Rabbit ADRA1B (100008731), sheep ADRA1B (101114869), cow ADRA1B (407140)
UniProtKB ID:
P35368, B0LPE1
Gene ID:
  • Human(147) Summary: Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1B-adrenergic receptor, which induces neoplastic transformation when transfected into NIH 3T3 fibroblasts and other cell lines. Thus, this normal cellular gene is identified as a protooncogene. This gene comprises 2 exons and a single large intron of at least 20 kb that interrupts the coding region. [provided by RefSeq, Jul 2008]
  • Mouse(11548) adrenergic receptor, alpha 1b
  • Rat(24173) adrenoceptor alpha 1B
  • domestic guinea pig(100735480) adrenoceptor alpha 1B
  • domestic cat(101092238) adrenoceptor alpha 1B
  • dog(403962) adrenoceptor alpha 1B
  • chicken(373890) adrenergic, alpha-1B-, receptor
  • Domestic Rabbit(100008731) adrenoceptor alpha 1B
  • sheep(101114869) adrenoceptor alpha 1B
  • cow(407140) adrenergic, alpha-1B-, receptor

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Small Molecule - Agonist

Product Number
Description
Species
CDS000481
3-[(1R)-1-Hydroxy-2-(methylamino)ethyl]phenol, AldrichCPR,
Species
human
A0232
Alfuzosin hydrochloride, ≥98% (HPLC), solid,
Species
human
1012917
Alfuzosin hydrochloride, United States Pharmacopeia (USP) Reference Standard,
Species
human
M6524
Methoxamine hydrochloride, ,
Species
human
P1250000
Phenylephrine hydrochloride, European Pharmacopoeia (EP) Reference Standard,
Species
human

Small Molecule - Antagonist

Product Number
Description
Species
N158
Naftopidil hydrochloride hydrate, solid,
Species
human
B016
Benoxathian hydrochloride, solid,
Species
human
T4680
Terazosin hydrochloride, ≥98% (TLC), powder,
Species
human
1643452
Terazosin hydrochloride, United States Pharmacopeia (USP) Reference Standard,
Species
human
PHR1721
Terazosin Hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
SAB2900164
Anti-ADRA1B (AB1) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
bovine, dog, hamster, horse, human, monkey, mouse, pig, rat
Application
ELISA
immunohistochemistry
SAB2900165
Anti-ADRA1B (AB2) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunohistochemistry
SAB4500521
Anti-ADRA1B antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence
HPA074416
Anti-ADRA1B antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence

esiRNA

Product Number
Description
Species
EHU054451
MISSION® esiRNA, targeting human ADRA1B,
Species
human