1.18305

Hexane-1-sulfonic acid sodium salt

for ion pair chromatography LiChropur^™

• Synonym(s): Hexane-1-sulfonic acid sodium salt
• Empirical Formula (Hill Notation): C₆H₁₃NaO₃S
• CAS Number: 2832-45-3
• Molecular Weight: 188.22
• MDL number: MFCD00007542
• UNSPSC Code: 12352107
• EC Index Number: 220-601-3
• NACRES: NB.21

Properties

• Quality Level: 100
• Assay: ≥99% (acidimetric)
• technique(s): ion pair chromatography: suitable
• loss: ≤2 loss on drying, 120°C; 4h; vacuum
• transmittance: 200 nm, ≥70%; 220 nm, ≥90%; 250 nm, ≥98%; (0.005 M; 1 cm in H₂O)
• pH: 5.5-7.5 (20 °C, 100 g/L in H₂O)
• suitability: passes test for identity (IR)
• storage temp.: 15-25°C
• InChI: 1S/C6H14O3S.Na/c1-2-3-4-5-6-10(7,8)9;/h2-6H2,1H3,(H,7,8,9);/q;+1/p-1
• InChI key: QWSZRRAAFHGKCH-UHFFFAOYSA-M

Description

General description

Hexane-1-sulfonicacid sodium salt is a commonly used ion-pair reagent in ion-pairchromatography. It is used as an ion-pair reagent to generate neutralequilibrium with the analytes, leading to increased retention and improvedseparation during the chromatographic analysis.

Application

Hexane-1-sulfonic acid sodium salt can be used as a:

• Part of the mobile phase composition in an HPLC stability-indicating method for the simultaneous determination of water-soluble vitamins and preservatives.
• Buffer component in a reverse-phase ultra-performance liquid chromatography (UPLC) method for the simultaneous determination of Sitagliptin phosphate monohydrate and Metformin hydrochloride in pharmaceutical dosage forms.

Legal Information

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 2
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable