928275
Gold nanoparticles
20 nm diameter, azide functionalized, 1ml, OD 50, in water
Synonym(s):
AuNP, GdNP, Gold NP
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About This Item
UNSPSC Code:
12141717
NACRES:
NA.22
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Quality Level
description
Alkyne surface density: 1/nm2
concentration
in water
OD
50
core diam.
20 nm , coefficient of variance <12%
diameter
20 nm
λmax
524 nm
PDI
<0.200
functional group
azide
storage temp.
2-8°C
InChI
1S/Au
InChI key
PCHJSUWPFVWCPO-UHFFFAOYSA-N
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General description
Azide functionalized gold nanoparticles are suitable for covalent conjugation of any molecule with a terminal alkyne through click chemistry. These gold nanoparticles allow for rapid generation of gold conjugates for subsequent use in downstream assays.
Azide functionalized gold nanoparticles are more than 95% spherical and have uniform size distribution (CV <12%).
Azide functionalized gold nanoparticles are more than 95% spherical and have uniform size distribution (CV <12%).
Application
Ideal for development of gold conjugates for use in applications such as blotting, lateral flow assays, microscopy, and transmission electron microscopy (TEM).
Storage and Stability
When stored for a long period of time gold nanoparticles may sediment at the bottom of the vial, which is especially prominent for larger particle sizes. Prior to use, re-suspend the sedimented particles by thorough mixing until a homogenous solution is obtained.
Storage Class Code
12 - Non Combustible Liquids
WGK
WGK 2
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Jennifer L Brennan et al.
Bioconjugate chemistry, 17(6), 1373-1375 (2006-11-16)
A simple and versatile method for the preparation of functional enzyme-gold nanoparticle conjugates using "click" chemistry has been developed. In a copper-catalyzed 1,2,3-triazole cycloaddition, an acetylene-functionalized Thermomyces lanuginosus lipase has been attached to azide-functionalized water-soluble gold nanoparticles under retention of
Vivek Poonthiyil et al.
Beilstein journal of organic chemistry, 14, 11-24 (2018-01-31)
Glycoscience, despite its myriad of challenges, promises to unravel the causes of, potential new detection methods for, and novel therapeutic strategies against, many disease states. In the last two decades, glyco-gold nanoparticles have emerged as one of several potential new
Monika Fischler et al.
Chemical communications (Cambridge, England), (2), 169-171 (2007-12-20)
We present a new type of azide-functionalized gold nanoparticle and their coupling to an alkyne-modified DNA duplex using the copper(I)-catalyzed Huisgen cycloaddition ('click chemistry'), resulting in a chain-like assembly of nanoparticles on the DNA template.
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