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Key Documents

SMB00976

Sigma-Aldrich

Malondialdehyde potassium salt enolate

≥95% (HPLC)

Synonym(s):

MDA potassium salt enolate

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About This Item

Empirical Formula (Hill Notation):
C3H3KO2
Molecular Weight:
110.15
NACRES:
NA.77

Quality Level

Assay

≥95% (HPLC)

form

solid

shipped in

wet ice

storage temp.

2-8°C

General description

Malondialdeyde is a biomarker of oxidative damage to lipids caused by smoking. Oxidized lipids are able to produce MDA as a decomposition product. While oxidation of polyunsaturated fatty acids is the major source of MDA in vivo, other minor sources exists such as byproducts of free radical generation by ionizing radiation and of the biosynthesis of prostaglandins.

Application

Metabolomics research

Other Notes

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Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Jens Lykkesfeldt
Clinica chimica acta; international journal of clinical chemistry, 380(1-2), 50-58 (2007-03-06)
Thiobarbituric acid reactive substances (TBARS) and malondialdehyde (MDA) have been used as biomarkers of lipid oxidation for more than thirty years. The validity of these biomarkers has been rightfully criticized for a lack of specificity and problems with post sampling
Flore Duranton et al.
Journal of the American Society of Nephrology : JASN, 23(7), 1258-1270 (2012-05-26)
An updated review of the existing knowledge regarding uremic toxins facilitates the design of experimental studies. We performed a literature search and found 621 articles about uremic toxicity published after a 2003 review of this topic. Eighty-seven records provided serum

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