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253847

Sigma-Aldrich

2,3,4-Trihydroxybenzoic acid

97%

Synonym(s):

Pyrogallol-4-carboxylic acid

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About This Item

Linear Formula:
(HO)3C6H2CO2H
CAS Number:
Molecular Weight:
170.12
Beilstein:
2210807
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Assay

97%

mp

~205 °C (dec.) (lit.)

SMILES string

OC(=O)c1ccc(O)c(O)c1O

InChI

1S/C7H6O5/c8-4-2-1-3(7(11)12)5(9)6(4)10/h1-2,8-10H,(H,11,12)

InChI key

BRRSNXCXLSVPFC-UHFFFAOYSA-N

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General description

DPPH radical-scavenging ability of 2,3,4-trihydroxybenzoic acid has been evaluated.

Application

2,3,4-Trihydroxybenzoic acid has been used as:
  • reagent during catalytic spectrophotometric determination of vanadium in natural and sea waters
  • internal standard in separation of phenolic acids by HPLC with photodiode array detection

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Rebecca J Robbins et al.
Journal of chromatography. A, 1038(1-2), 97-105 (2004-07-06)
A quantitative high-performance liquid chromatography-photodiode array detection method separating 16 phenolic acids was achieved. Six columns and several mobile phases were investigated. Resolution was achieved with a high-purity silica Phenomenex Luna C18 column (150 mm x 4.6 mm, 5 microm)
David V McCalley
Journal of chromatography. A, 1483, 71-79 (2017-01-11)
Trifluoracetic acid (TFA) added to the aqueous acetonitrile mobile phase induces some unexpected changes in the ionic component of retention in hydrophilic interaction separations when using Type B silica and amide-bonded silica columns. TFA use results in anion exchange properties
A A Mohamed et al.
Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 17(6), 769-773 (2001-11-16)
A new, simple, sensitive and selective catalytic method is developed for the determination of vanadium in natural and sea waters. The method is based on the catalytic effect of V(V) and/or V(IV) on the bromate oxidative-coupling reaction of metol with
F Ramezani Ali Akbari et al.
Acta endocrinologica (Bucharest, Romania : 2005), 15(2), 187-194 (2019-09-12)
Endothelial dysfunction and diabetic cardiomyopathy are critical complications of diabetes. Gallic acid (GA) plays a significant role in cardiovascular disorders resulted from diabetes. In addition, increased plasma miR-24, miR-126 associated with endothelial dysfunction. The current study was designed to assess
Yaghoob Farbood et al.
Avicenna journal of phytomedicine, 3(4), 329-340 (2014-07-23)
It is generally agreed that most of the phenomena observed during brain ischemia and reperfusion can be explained by the damage to membrane structure. Oxidative stress is resulted in an imbalance between high consumption of oxygen and low levels of

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