MAB344
Anti-O1 Antibody, clone 59
clone 59, Chemicon®, from mouse
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About This Item
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biological source
mouse
Quality Level
antibody form
saturated ammonium sulfate (SAS) precipitated
clone
59, monoclonal
species reactivity
chicken, rat, mouse, human
manufacturer/tradename
Chemicon®
technique(s)
immunohistochemistry: suitable
isotype
IgM
shipped in
wet ice
target post-translational modification
unmodified
Specificity
Recognizes Oligodendrocyte marker O1. Also reacts with certain galactolipids in sperm (see Additional Information library for list).
Immunogen
White matter of corpus callosum from rat brain.
Application
Anti-O1 Antibody, clone 59 is an antibody against O1 for use in IH.
Immunohistochemistry: 10-20 μg/mL on unfixed, shock frozen tissue.
Note: 01 is a lipid which is released from the membrane by alcohol.
Optimal working dilutions must be determined by the end user.
Note: 01 is a lipid which is released from the membrane by alcohol.
Optimal working dilutions must be determined by the end user.
Research Category
Neuroscience
Neuroscience
Research Sub Category
Neuronal & Glial Markers
Neuronal & Glial Markers
Physical form
Format: Purified
Liquid. Buffer = 0.05 M Potassium Phosphate, 0.3 M NaCl, pH 8.0 with 0.05% sodium azide.
Storage and Stability
Maintain lyophilized material at +2–8°C for up to 12 months. After reconstitution maintain frozen at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles.
Analysis Note
Control
Oligodendrocyte culture, Brain
Oligodendrocyte culture, Brain
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage Class Code
10 - Combustible liquids
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Find documentation for the products that you have recently purchased in the Document Library.
Folia neuropathologica, 57(1), 24-35 (2019-05-01)
This study was performed to determine whether the disturbed maturation of oligodendrocyte (OL) progenitors might be related to lipopolysaccharide (LPS)-induced hypomyelination. We created organotypic cultures of forebrain slices from neonatal rats and explored the morphological changes of glial cells expressing
Generation of functional neurons and glia from multipotent adult mouse germ-line stem cells.
Stem Cell Research, 2, 139-154 (2009)
Molecular neurobiology (2016-01-10)
Studies have shown that progesterone enhances functional recovery after ischemic stroke, but the underlying mechanisms are not completely understood. Therefore, we investigated the effect of progesterone on vascular endothelial growth factor (VEGF), brain-derived neurotrophic factor (BDNF), and neurogenesis in a
Olfactory ensheathing cells exhibit unique migratory, phagocytic, and myelinating properties in the X-irradiated spinal cord not shared by Schwann cells.
Glia null
Immuno-electron-microscopic identification of O-antigen-bearing oligodendroglial cells in vitro
Cell and Tissue Research, 219, 313-325 (1981)
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