D-013

Dextromethorphan solution

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant^®

• Empirical Formula (Hill Notation): C₁₈H₂₅NO
• CAS Number: 125-71-3
• Molecular Weight: 271.40
• MDL number: MFCD00866833
• UNSPSC Code: 41116107
• PubChem Substance ID: 329798586
• NACRES: NA.24

Properties

• grade: certified reference material
• form: liquid
• feature: Snap-N-Spike^®/Snap-N-Shoot^®
• packaging: ampule of 1 mL
• manufacturer/tradename: Cerilliant^®
• concentration: 1.0 mg/mL in methanol
• technique(s): gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• application(s): forensics and toxicology
• format: single component solution
• storage temp.: −20°C
• SMILES string: COc1ccc2C[C@H]3[C@H]4CCCC[C@@]4(CCN3C)c2c1
• InChI: 1S/C18H25NO/c1-19-10-9-18-8-4-3-5-15(18)17(19)11-13-6-7-14(20-2)12-16(13)18/h6-7,12,15,17H,3-5,8-11H2,1-2H3/t15-,17+,18+/m1/s1
• InChI key: MKXZASYAUGDDCJ-NJAFHUGGSA-N
• Gene Information: human ... GRIN2A(2903) , SIGMAR1(10280)

Description

General description

Dextromethorphan is an opiate analgesic sold as an antitussive under trade names such as Robitussin^®, NyQuil^®, or Dimetapp^®. Also known as DXM, the drug is used recreationally as a hallucinogen with effects similar to ketamine and phencyclidine (PCP). This Certified Snap-N-Spike^® Solution is suitable for use as starting material in calibrators or controls for a variety of LC/MS or GC/MS applications from forensic analysis and clinical toxicology to P450 trials and pharmaceutical research.

Application

• Voriconazole-D3 isotopic label: It is used to develop a method for the simultaneous determination of voriconazole and its metabolite, voriconazole N-oxide, in human urine using liquid chromatography/tandem mass spectrometry. This study highlights the application of voriconazole-D3 as a stable isotope-labeled internal standard, crucial for accurate quantification and monitoring of drug metabolism in clinical pharmacokinetic studies (Yu et al., 2022).

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Dimetapp is a registered trademark of Wyeth LLC

NyQuil is a registered trademark of Procter & Gamble Co.

Robitussin is a registered trademark of Wyeth LLC

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Pictograms: GHS02,GHS06,GHS08
• Signal Word: Danger
• Hazard Statements: H225,H301 + H311 + H331,H370
• Precautionary Statements: P210 - P233 - P280 - P301 + P310 - P303 + P361 + P353 - P304 + P340 + P311
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• Target Organs: Eyes,Central nervous system
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 2
• Flash Point(F): 51.8 °F - closed cup
• Flash Point(C): 11.0 °C - closed cup