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Key Documents

719846

Sigma-Aldrich

Resomer® X 206 S, poly(dioxanone)

Synonym(s):

PDS

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About This Item

Linear Formula:
(C4H6O3)n
CAS Number:
MDL number:
UNSPSC Code:
12162002
NACRES:
NA.23

form

solid

degradation timeframe

<6 months

inherent viscosity

1.5-2.2 dL/g, 0.1 % (w/v) in hexafluoroisopropanol(30 °C, Ubbelohde) (size 0c glass capillary viscometer)

transition temp

Tg −10-−5 °C
Tm 110-115 °C

storage temp.

−20°C

InChI

1S/C4H6O3/c5-4-3-6-1-2-7-4/h1-3H2

InChI key

VPVXHAANQNHFSF-UHFFFAOYSA-N

General description

Polydioxanone (PDO) is a colorless, crystalline, highly flexible and resorbable biopolymer.

Application

PDO is widely used as a monofilament wound suture. PDO/elastin-based blends prepared by electrospinning may be used as cardiovascular grafts.

Legal Information

Product of Evonik
RESOMER is a registered trademark of Evonik Rohm GmbH

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Xin-miao Huang et al.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 81(2), 324-330 (2012-08-14)
This study evaluated the feasibility, effectiveness, and safety of a biodegradable (BD) occluder for closure of ventricular septal defect (VSD) in an acute canine model. All current available VSD occluders are permanent implants which consist of a metal framework and
Koyal Garg et al.
Biomaterials, 34(18), 4439-4451 (2013-03-22)
In this study, we investigated the effect of fiber and pore size of an electrospun scaffold on the polarization of mouse bone marrow-derived macrophages (BMMΦs) towards regenerative (M2) or inflammatory (M1) phenotypes. BMMΦs were seeded on Polydioxanone (PDO) scaffolds electrospun
Tissue hyperplasia following placement of a biodegradable stent for a refractory esophageal stricture: treatment with argon plasma coagulation.
F L Dumoulin et al.
Endoscopy, 44 Suppl 2 UCTN, E356-E357 (2012-10-04)
Christian Conderman et al.
The Laryngoscope, 123(2), 339-343 (2012-09-12)
This study attempts to characterize the biomechanical properties of a PDS-cartilage composite graft for use in septorhinoplasty. Experimental Study. This study used a PDS analog, porcine cartilage cut to 1 × 5 × 20 mm, and a mechanical testing platform
Marcus Gerressen et al.
Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 70(10), 2375-2385 (2012-07-10)
Although orbital floor fractures are frequently treated by the Ethisorb patch or polydioxanone foil, the utility of these treatments in extensive fractures remains controversial. The purpose of this study was to examine objectively the extent to which such flexible absorbable

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