Sulindac hepatotoxicity: a case report and review.

Sulindac hepatotoxicity: a case report and review.

Journal of toxicology. Clinical toxicology (1985-01-01)

A G Gallanosa, D A Spyker

ABSTRACT

A 44 year old female, previously on propranolol, phenytoin and phenobarbital, developed hepatotoxicity while on sulindac and acetaminophen containing analgesic. A limited review of hepatotoxicity and drug interactions of sulindac is presented. The possible mechanism of hepatotoxicity and its treatment is suggested.

MATERIALS

Product Number

Brand

Product Description

S2180000

Sulindac, European Pharmacopoeia (EP) Reference Standard

S8139

Sigma-Aldrich

Sulindac, ≥98.0%