Y0000227
Meso-rich exametazime
European Pharmacopoeia (EP) Reference Standard
Synonym(s):
Exametazime
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About This Item
Empirical Formula (Hill Notation):
C13H28N4O2
CAS Number:
Molecular Weight:
272.39
UNSPSC Code:
41116107
NACRES:
NA.24
Recommended Products
grade
pharmaceutical primary standard
API family
meso-rich exametazime
manufacturer/tradename
EDQM
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-8°C
InChI
1S/C13H28N4O2/c1-9(11(3)16-18)14-7-13(5,6)8-15-10(2)12(4)17-19/h9-10,14-15,18-19H,7-8H2,1-6H3/b16-11+,17-12+/t9-,10-/m1/s1
InChI key
BPNZYADGDZPRTK-UDUYQYQQSA-N
General description
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
Application
Meso-rich exametazime EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.
Packaging
The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.
Other Notes
Sales restrictions may apply.
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K T Cheng et al.
American journal of hospital pharmacy, 49(8), 1950-1954 (1992-08-01)
The effect of exametazime concentration, storage time, and the volume of the radiolabeling compound on the radiochemical purity of labeled exametazime doses was studied. Exametazime cold unit doses (CUDs) of 0.50, 0.33, 0.25, 0.17, and 0.13 mg/mL were prepared by
John T O'Brien et al.
NeuroImage, 40(3), 1056-1063 (2008-02-26)
To investigate in vivo differences in the distribution of alpha4beta2 subtypes of nAChR using the ligand (123)I-5-Iodo-3-[2(S)-2-azetidinylmethoxy] pyridine (5IA-85380) and single photon emission computed tomography (SPECT) in DLB and similarly aged controls. Thirty-one subjects (15 DLB and 16 controls) underwent
J W Fletcher et al.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 35(12), 2003-2010 (1994-12-01)
A method for developing diagnostic practice guidelines is presented in which a team of experts used a semiquantitative scoring system to reach consensus on a standard procedure for SPECT cerebral perfusion imaging. An expert panel generated a list of elements
N Nikolić et al.
Journal of pharmaceutical and biomedical analysis, 34(2), 285-293 (2004-03-12)
99M Tc (V)-d,l-HM-PAO complex is well-known radiopharmaceutical for regional cerebral blood flow imaging. The proposed modifications in exametazime, hexamethylpropyleneamine oxime (HM-PAO) (4,8-diaza-3,6,6,9-tetramethylundecane-2,10-dione bisoxime) synthesis, for reduction of intermediary reactant diiminebisoxime (DI) (4,8-diaza-3,6,6,9-tetramethylundecane-3,8-diene-2,10-dione bisoxime) concerned two reductants (NaBH(4) and KBH(4)), two
N Nikolić et al.
Journal of pharmaceutical and biomedical analysis, 32(6), 1159-1166 (2003-08-09)
The diastereo-enantio separation of isomeric mixtures of exametazime (HM-PAO) by liquid chromatography is described using an achiral sorbent (RP-18). A chiral eluent with the initial complex of Cu(II) and the optically active selector N,N-dimethyl-l-phenylalanine (l-DM-PhA), based on the ligand-exchange principle
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