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Key Documents

861448

Sigma-Aldrich

8-Azaguanine

98%

Synonym(s):

2-Amino-6-hydroxy-8-azapurine, 2-Amino-6-oxy-8-azapurine, Guanazolo

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About This Item

Empirical Formula (Hill Notation):
C4H4N6O
CAS Number:
Molecular Weight:
152.11
Beilstein:
171098
EC Number:
MDL number:
UNSPSC Code:
12352200

Assay

98%

mp

>300 °C (lit.)

SMILES string

NC1=Nc2[nH]nnc2C(=O)N1

InChI

1S/C4H4N6O/c5-4-6-2-1(3(11)7-4)8-10-9-2/h(H4,5,6,7,8,9,10,11)

InChI key

LPXQRXLUHJKZIE-UHFFFAOYSA-N

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Y Xiao et al.
Hunan yi ke da xue xue bao = Hunan yike daxue xuebao = Bulletin of Hunan Medical University, 22(2), 113-115 (1997-01-01)
A human lung cancer cell line (A549) mutant with hypoxanthine guanine phosphoribosyltransferase (HGPRT) deficiency and resistance to 8-AG was established by treatment of the A549 cells with 3 micrograms.ml-1 N-methyl-N'-nitro-nitrosoguanidine (MNNG), and prescreened in 0.25% agarose DMEM semisolid medium containing
F R Ridzlan et al.
Tropical biomedicine, 27(3), 632-638 (2011-03-15)
Leptospirosis is recognized as one of the important zoonotic diseases in the world including Malaysia. A total of 145 soil and water samples were collected from selected National Service Training Centres (NSTC) in Kelantan and Terengganu. The samples were inoculated
Bashir Mir et al.
Nucleic acids research, 32(3), e25-e25 (2004-02-13)
The use of primary somatic cells in nuclear transfer procedure has opened a new opportunity to manipulate domestic animal genomes via homologous recombination. To date, while a few loci have been targeted in somatic cells using similar enrichment strategies as
J H Park et al.
Hybridoma, 16(6), 551-556 (1998-02-10)
Macrophages are important constituents of the immune system by exerting phagocytosis on invading pathogens as well as secreting various immunoregulatory factors. Generation of human macrophage hybridoma has not been possible so far due to the lack of an appropriate fusion
Yan-li Wei et al.
Guang pu xue yu guang pu fen xi = Guang pu, 24(7), 862-866 (2005-03-16)
The inclusion complexes of beta-Cyclodextrin (beta-CD) and HP-beta-Cyclodextrin (HP-beta-CD) with 6-Mercaptopurine (6-MP), Azathioprine (BAN) and 8-Azaguanine (Azan) were investigated by fluorescence. Various factors affecting the formation of inclusion complexes were discussed in detail including formation time and pH effect. The

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