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Merck

XRCC4

X-ray repair complementing defective repair in Chinese hamster cells 4

Synonyms:
Species:
UniProtKB ID:
Gene ID:
  • Human(7518) Summary: The protein encoded by this gene functions together with DNA ligase IV and the DNA-dependent protein kinase in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. The non-homologous end-joining pathway is required both for normal development and for suppression of tumors. This gene functionally complements XR-1 Chinese hamster ovary cell mutant, which is impaired in DNA double-strand breaks produced by ionizing radiation and restriction enzymes. Alternative transcription initiation and alternative splicing generates several transcript variants. [provided by RefSeq, Sep 2008]
  • Mouse(108138) X-ray repair complementing defective repair in Chinese hamster cells 4
  • Rat(309995) X-ray repair complementing defective repair in Chinese hamster cells 4
  • chicken(427325) X-ray repair complementing defective repair in Chinese hamster cells 4
  • dog(488923) X-ray repair complementing defective repair in Chinese hamster cells 4
  • Zebrafish(393759) X-ray repair complementing defective repair in Chinese hamster cells 4
  • domestic guinea pig(100731158) X-ray repair complementing defective repair in Chinese hamster cells 4
  • sheep(101102481) X-ray repair complementing defective repair in Chinese hamster cells 4
  • naked mole-rat(101709691) X-ray repair complementing defective repair in Chinese hamster cells 4
  • cow(613590) X-ray repair complementing defective repair in Chinese hamster cells 4
  • Thale Cress(821885) DNA repair protein XRCC4-like protein

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-XRCC4 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

western blot
Anti-XRCC4 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
ELISA
western blot
Anti-XRCC4 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human, mouse
Application
western blot
Anti-XRCC4 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

western blot
Anti-XRCC4 antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
immunofluorescence
immunohistochemistry

western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human XRCC4,
Species
human
MISSION® esiRNA, targeting mouse Xrcc4,
Species
mouse