RFC5
replication factor C (activator 1) 5, 36.5kDa
Synonyms:
RFC36
Species:
Human RFC5 (5985), Mouse Rfc5 (72151), Rat Rfc5 (304528), domestic cat RFC5 (101092297), Zebrafish rfc5 (445385), naked mole-rat Rfc5 (101710167), sheep RFC5 (101109740), domestic guinea pig Rfc5 (100723132), Horse RFC5 (100054946), dog RFC5 (477499) ...More
UniProtKB ID:
Gene ID:
- Human(5985) Summary: The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also named activator 1, is a protein complex consisting of five distinct subunits of 140, 40, 38, 37, and 36 kD. This gene encodes the 36 kD subunit. This subunit can interact with the C-terminal region of PCNA. It forms a core complex with the 38 and 40 kDa subunits. The core complex possesses DNA-dependent ATPase activity, which was found to be stimulated by PCNA in an in vitro system. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 9. [provided by RefSeq, May 2011]
- Mouse(72151) replication factor C (activator 1) 5
- Rat(304528) replication factor C (activator 1) 5
- domestic cat(101092297) replication factor C (activator 1) 5, 36.5kDa
- Zebrafish(445385) replication factor C (activator 1) 5
- naked mole-rat(101710167) replication factor C (activator 1) 5, 36.5kDa
- sheep(101109740) replication factor C (activator 1) 5, 36.5kDa
- domestic guinea pig(100723132) replication factor C (activator 1) 5, 36.5kDa
- Horse(100054946) replication factor C (activator 1) 5, 36.5kDa
- dog(477499) replication factor C (activator 1) 5, 36.5kDa
- cow(508389) replication factor C (activator 1) 5, 36.5kDa
- Domestic Rabbit(100345366) replication factor C (activator 1) 5, 36.5kDa
- chicken(100859719) replication factor C (activator 1) 5, 36.5kDa
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Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-RFC5 antibody produced in mouse, clone 1B1, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence
western blot
immunofluorescence
western blot
Anti-RFC5 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-RFC5 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot