PIK3CB
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
Synonyms:
P110BETA, PI3K, PI3KBETA, PIK3C1
Species:
Human PIK3CB (5291), Mouse Pik3cb (74769), Rat Pik3cb (85243), dog PIK3CB (477085), naked mole-rat Pik3cb (101715249), domestic cat PIK3CB (101091892), sheep PIK3CB (101109759), cow PIK3CB (517948), Zebrafish pik3cb (100002263), chicken PIK3CB (424826) ...More
UniProtKB ID:
Gene ID:
- Human(5291) Summary: This gene encodes an isoform of the catalytic subunit of phosphoinositide 3-kinase (PI3K). These kinases are important in signaling pathways involving receptors on the outer membrane of eukaryotic cells and are named for their catalytic subunit. The encoded protein is the catalytic subunit for PI3Kbeta (PI3KB). PI3KB has been shown to be part of the activation pathway in neutrophils which have bound immune complexes at sites of injury or infection. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2011]
- Mouse(74769) phosphatidylinositol 3-kinase, catalytic, beta polypeptide
- Rat(85243) phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
- dog(477085) phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
- naked mole-rat(101715249) phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
- domestic cat(101091892) phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
- sheep(101109759) phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
- cow(517948) phosphoinositide-3-kinase, catalytic, beta polypeptide
- Zebrafish(100002263) phosphoinositide-3-kinase, catalytic, beta polypeptide
- chicken(424826) phosphoinositide-3-kinase, catalytic, beta polypeptide
- Horse(100051753) phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
- Domestic Rabbit(100345181) phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
- domestic guinea pig(100727986) phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
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Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-PIK3CB antibody produced in mouse, clone 10D5, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence
proximity ligation assay
western blot
immunofluorescence
proximity ligation assay
western blot
Anti-PI3 Kinase p110 β Antibody, clone 1D18 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human, monkey, porcine
Application
affinity binding assay
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-PIK3CB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
western blot
western blot
Anti-PIK3CB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
Anti-PI3 Kinase Antibody, p110β, from rabbit, purified by affinity chromatography,
Species Reactivity
canine, dog, human, monkey, mouse, rat
Application
ELISA
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
western blot
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
western blot
Small Molecule - Inhibitor
Product Number
Description
Species
Proteins
Product Number
Description
Species
PI3K (p110-β/p85-β), active, His tagged human, PRECISIO®, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human