ERBB4
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 4
Synonyms:
HER4, p180erbB4
Species:
Human ERBB4 (2066), Mouse Erbb4 (13869), Rat Erbb4 (59323), naked mole-rat Erbb4 (101725806), domestic guinea pig Erbb4 (100724678), Domestic Rabbit ERBB4 (100009328), sheep ERBB4 (101103044), cow ERBB4 (522419), Horse ERBB4 (100050182), domestic cat ERBB4 (101100073) ...More
UniProtKB ID:
Gene ID:
- Human(2066) Summary: This gene is a member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily. It encodes a single-pass type I membrane protein with multiple cysteine rich domains, a transmembrane domain, a tyrosine kinase domain, a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif. The protein binds to and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation. Multiple proteolytic events allow for the release of a cytoplasmic fragment and an extracellular fragment. Mutations in this gene have been associated with cancer. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008]
- Mouse(13869) v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)
- Rat(59323) v-erb-b2 avian erythroblastic leukemia viral oncogene 4
- naked mole-rat(101725806) v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)
- domestic guinea pig(100724678) v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)
- Domestic Rabbit(100009328) v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)
- sheep(101103044) v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)
- cow(522419) v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 4
- Horse(100050182) v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)
- domestic cat(101100073) v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)
- dog(488508) v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)
- chicken(395671) v-erb-a erythroblastic leukemia viral oncogene homolog 4
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
ELISA
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-Phospho-ERBB4-Y1284 antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
western blot
Anti-erbB4 Antibody, clone HFR1/2G4, clone HFR1/2G4, from mouse,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-ErbB4/HER4 Antibody, clone 8E5D0, Rabbit Monoclonal, ,
Species Reactivity
mouse, rat
Application
western blot
Anti-erbB4/HER4 Antibody, clone 1B7 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human, mouse, rat
Application
affinity binding assay
flow cytometry
immunocytochemistry
immunohistochemistry
western blot
flow cytometry
immunocytochemistry
immunohistochemistry
western blot
Anti-ERBB4 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Small Molecule - Inhibitor
Proteins
Product Number
Description
Species
ErbB4 Protein, active, 10 µg, Active, N-Terminal His6-tagged, recombinant, human ErbB4 amino acids 706-991, for use in Kinase Assays.,
Species
human