Skip to Content
Merck

COPS4

COP9 signalosome subunit 4

Synonyms:
CSN4
Species:
UniProtKB ID:
Gene ID:
  • Human(51138) Summary: This gene encodes one of eight subunits composing COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]
  • Mouse(26891) COP9 (constitutive photomorphogenic) homolog, subunit 4 (Arabidopsis thaliana)
  • Rat(360915) COP9 signalosome subunit 4
  • domestic cat(101085203) COP9 constitutive photomorphogenic homolog subunit 4 (Arabidopsis)
  • Zebrafish(325592) COP9 constitutive photomorphogenic homolog subunit 4 (Arabidopsis)
  • chicken(422594) COP9 constitutive photomorphogenic homolog subunit 4 (Arabidopsis)
  • domestic guinea pig(100722440) COP9 signalosome subunit 4
  • naked mole-rat(101719262) COP9 signalosome subunit 4
  • Horse(100052196) COP9 constitutive photomorphogenic homolog subunit 4 (Arabidopsis)
  • cow(540223) COP9 constitutive photomorphogenic homolog subunit 4 (Arabidopsis)
  • sheep(101117334) COP9 constitutive photomorphogenic homolog subunit 4 (Arabidopsis)
  • dog(478455) COP9 constitutive photomorphogenic homolog subunit 4 (Arabidopsis)

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-COPS4 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human, rat
Application
immunohistochemistry
western blot
Anti-COPS4 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Cops4,
Species
mouse
MISSION® esiRNA, targeting human COPS4,
Species
human