CCNT1
cyclin T1
Synonyms:
CCNT, CYCT1, HIVE1
Species:
Human CCNT1 (904), Mouse Ccnt1 (12455), Rat Ccnt1 (315291), Zebrafish ccnt1 (334465), dog CCNT1 (486564), chicken CCNT1 (100859215), sheep CCNT1 (101106415), domestic cat CCNT1 (101090703), cow CCNT1 (407194), naked mole-rat Ccnt1 (101700254) ...More
UniProtKB ID:
Gene ID:
- Human(904) Summary: This gene encodes a member of the highly conserved cyclin C subfamily. The encoded protein tightly associates with cyclin-dependent kinase 9, and is a major subunit of positive transcription elongation factor b (p-TEFb). In humans, there are multiple forms of positive transcription elongation factor b, which may include one of several different cyclins along with cyclin-dependent kinase 9. The complex containing the encoded cyclin and cyclin-dependent kinase 9 acts as a cofactor of human immunodeficiency virus type 1 (HIV-1) Tat protein, and is both necessary and sufficient for full activation of viral transcription. This cyclin and its kinase partner are also involved in triggering transcript elongation through phosphorylation of the carboxy-terminal domain of the largest RNA polymerase II subunit. Overexpression of this gene is implicated in tumor growth. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2013]
- Mouse(12455) cyclin T1
- Rat(315291) cyclin T1
- Zebrafish(334465) cyclin T1
- dog(486564) cyclin T1
- chicken(100859215) cyclin T1
- sheep(101106415) cyclin T1
- domestic cat(101090703) cyclin T1
- cow(407194) cyclin T1
- naked mole-rat(101700254) cyclin T1
- Horse(100033893) cyclin T1
- domestic guinea pig(100731674) cyclin T1
- Domestic Rabbit(100352150) cyclin T1
- Goat(100860835) cyclin T1
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-CCNT1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human, mouse, rat
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-CCNT1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
western blot
western blot
Anti-CCNT1 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
immunofluorescence
western blot
western blot
Anti-Cyclin T1 Antibody, serum, from sheep,
Species Reactivity
human, mouse
Application
western blot