- Single Walled Carbon Nanotubes/polypyrrole-GOx composite films to modify gold microelectrodes for glucose biosensors: Study of the extended linearity.
Single Walled Carbon Nanotubes/polypyrrole-GOx composite films to modify gold microelectrodes for glucose biosensors: Study of the extended linearity.
Biosensors & bioelectronics (2013-01-02)
F Valentini, L Galache Fernàndez, E Tamburri, G Palleschi
PMID23277343
ABSTRACT
A glucose biosensor was assembled using gold microelectrodes (diameter of 250 μm) coated by Single-Walled Carbon Nanotubes (SWCNTs), via the Electrophoresis Deposition Process (EPD). This nanostructured platform was successfully used to deposit the poly(pyrrole)/glucose oxidase film (PPy/GOx). The most important result of this biosensors was the wide linear range of concentration, ranging from 4 to100 mM (covering the hypo- and hyper-glycemia range, useful in diabetes). This extended linearity offered the possibility to measure glucose from 0.560 to 12.0 mM, with a detection limit of 50 μM (useful for hypo-glycemia disease).
MATERIALS
Product Number
Brand
Product Description
Sigma-Aldrich
Polypyrrole, doped, conductivity 0.5-1.5 S/cm (pressed pellet, typical), extent of labeling: ~5 wt. % loading, coated on titanium dioxide
Sigma-Aldrich
Polypyrrole, doped, conductivity 30 S/cm (bulk), extent of labeling: 20 wt. % loading, composite with carbon black