246328

6-Methylindole

97%

• Empirical Formula (Hill Notation): C₉H₉N
• CAS Number: 3420-02-8
• Molecular Weight: 131.17
• Beilstein: 109708
• MDL number: MFCD00005682
• UNSPSC Code: 12352100
• PubChem Substance ID: 24854801
• NACRES: NA.22

Properties

• Assay: 97%
• form: solid
• refractive index: n20/D 1.607 (lit.)
• bp: 112 °C/5 mmHg (lit.)
• density: 1.059 g/mL at 25 °C (lit.)
• SMILES string: Cc1ccc2cc[nH]c2c1
• InChI: 1S/C9H9N/c1-7-2-3-8-4-5-10-9(8)6-7/h2-6,10H,1H3
• InChI key: ONYNOPPOVKYGRS-UHFFFAOYSA-N

Description

Application

6-Methylindole was used in the synthesis of benz[c,d]indol-3(1H)-one derivatives.

• Reactant for preparation of tryptophan dioxygenase inhibitors pyridyl-ethenyl-indoles as potential anticancer immunomodulators
• Reactant for preparation of indole linked triazole derivatives as antifungal agents
• Reactant for preparation of N-β-D-xylosyl-indole derivatives as SGLT2 inhibitors for management of hyperglycemia in diabetes
• Reactant for preparation of aminoguanidine derivatives of arylsulfonylacylindoles as antifungal agents
• Reactant for preparation of indolylindazoles and indolylpyrazolopyridines as interleukin-2 inducible T cell kinase inhibitors
• Reactant for preparation of arylsulfonylacetylindoles as anti-HIV-1 agents

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H315,H319,H335
• Precautionary Statements: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): 230.0 °F - closed cup
• Flash Point(C): 110 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves