- Sodium channel Na
Sodium channel Na
Scientific reports (2017-11-17)
Peter R Strege, Kaitlyn Knutson, Samuel J Eggers, Joyce H Li, Fan Wang, David Linden, Joseph H Szurszewski, Lorin Milescu, Andrew B Leiter, Gianrico Farrugia, Arthur Beyder
PMID29142310
RESUMEN
In the gastrointestinal (GI) epithelium, enterochromaffin (EC) cells are enteroendocrine cells responsible for producing >90% of the body's serotonin (5-hydroxytryptamine, 5-HT). However, the molecular mechanisms of EC cell function are poorly understood. Here, we found that EC cells in mouse primary cultures fired spontaneous bursts of action potentials. We examined the repertoire of voltage-gated sodium channels (Na
MATERIALES
Referencia del producto
Marca
Descripción del producto
Sigma-Aldrich
Suero fetal bovino, USA origin, Heat Inactivated, sterile-filtered, suitable for cell culture, suitable for insect cell culture, suitable for hybridoma
Sigma-Aldrich
Medio de Eagle modificado de Dulbecco, glucosa elevada, With 4500 mg/L glucose, sodium pyruvate, and sodium bicarbonate, without L-glutamine, liquid, sterile-filtered, suitable for cell culture
Sigma-Aldrich
Colagenasa from Clostridium histolyticum, powder, Suitable for the digestion and isolation of physiologically active pancreatic islet cells, suitable for cell culture