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Characterization of Induced Pluripotent Stem Cell-derived Human Serotonergic Neurons.

Frontiers in cellular neuroscience (2017-05-24)
Lining Cao, Rui Hu, Ting Xu, Zhen-Ning Zhang, Weida Li, Jianfeng Lu
RESUMEN

In the brain, the serotonergic neurons located in the raphe nucleus are the unique resource of the neurotransmitter serotonin, which plays a pivotal role in the regulation of brain development and functions. Dysfunction of the serotonin system is present in many psychiatric disorders. Lack of